| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Harry Potter and the Goblet of Fire | $1,850,366 | -58.3% | 647 | -47 | $2,859 | $20,500,890 | 3 | Warner Bros. | false | false |
| 2 | 2 | Mr. & Mrs. Smith | $1,750,772 | -39.1% | 517 | - | $3,386 | $6,642,708 | 2 | 01 Distribution | false | false |
| 3 | 3 | Chicken Little | $1,562,088 | -22.8% | 479 | +5 | $3,261 | $5,228,511 | 2 | Buena Vista International | false | false |
| 4 | 5 | Broken Flowers | $449,708 | +0.7% | 129 | +43 | $3,486 | $1,279,989 | 2 | Mikado Film | false | false |
| 5 | 4 | Melissa P. | $358,571 | -48.9% | 184 | -41 | $1,948 | $6,876,461 | 4 | Sony Pictures Releasing | false | false |
| 6 | 7 | The Cave | $266,299 | -17.6% | 117 | +1 | $2,276 | $864,665 | 2 | Sony Pictures Releasing | false | false |
| 7 | 6 | Cry Wolf | $226,544 | -31.4% | 119 | -23 | $1,903 | $18,838,390 | 3 | Eagle Pictures | false | false |
| 8 | 9 | La seconda notte di nozze | $170,551 | -28% | 88 | -2 | $1,938 | $3,849,385 | 5 | 01 Distribution | false | false |
| 9 | 8 | March of the Penguins | $165,268 | -48.7% | 169 | -37 | $977 | $3,674,199 | 4 | Lucky Red | false | false |
| 10 | - | Assault on Precinct 13 | $147,749 | - | 110 | - | $1,343 | $175,108 | 1 | CDI Films | true | false |
| 11 | 10 | Crash | $145,782 | -1.8% | 73 | +14 | $1,997 | $1,919,708 | 5 | Filmauro | false | false |
| 12 | 11 | Lord of War | $90,890 | -19% | 69 | -7 | $1,317 | $1,461,115 | 4 | Italian International Film | false | false |
| 13 | 12 | Go for Zucker | $77,814 | -24.3% | 41 | +5 | $1,897 | $369,506 | 3 | Lady Film | false | false |
| 14 | - | The Child | $58,090 | - | 18 | - | $3,227 | $87,603 | 2 | BIM Distribuzione | false | false |
| 15 | 14 | The Interpreter | $55,593 | -13.1% | 23 | -4 | $2,417 | $6,726,536 | 7 | United International Pictures | false | false |
| 16 | - | Me and You and Everyone We Know | $54,756 | - | 11 | - | $4,977 | $80,988 | 1 | Eagle Pictures | true | false |
| 17 | 13 | Flightplan | $39,887 | -38.3% | 30 | -8 | $1,329 | $6,135,492 | 6 | Buena Vista International | false | false |
| 18 | 15 | Everything Is Illuminated | $28,993 | -23.3% | 14 | -1 | $2,070 | $330,770 | 5 | Warner Bros. | false | false |
| 19 | 16 | An Unfinished Life | $28,668 | -6.5% | 33 | +3 | $868 | $883,431 | 4 | Eagle Pictures | false | false |
| 20 | - | In Her Shoes | $28,208 | - | 21 | - | $1,343 | $1,264,682 | 5 | 20th Century Fox International | false | false |
