| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Longest Yard | $2,310,317 | - | 379 | - | $6,095 | $2,310,317 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | The 40-Year-Old Virgin | $1,837,955 | -43.2% | 394 | - | $4,664 | $6,645,745 | 2 | United International Pictures | false | false |
| 3 | 2 | Red Eye | $1,151,513 | -29.9% | 354 | - | $3,252 | $3,805,755 | 2 | United International Pictures | false | false |
| 4 | - | Cinderella Man | $1,131,513 | - | 391 | - | $2,893 | $1,131,513 | 1 | Buena Vista International | true | false |
| 5 | 3 | Charlie and the Chocolate Factory | $997,429 | -18% | 422 | -35 | $2,363 | $66,145,739 | 7 | Warner Bros. | false | false |
| 6 | - | Green Street Hooligans | $821,498 | - | 245 | - | $3,353 | $821,498 | 1 | United International Pictures | true | false |
| 7 | 8 | Herbie Fully Loaded | $698,956 | +20.4% | 371 | -34 | $1,883 | $10,987,351 | 6 | Buena Vista International | false | false |
| 8 | 4 | The Dukes of Hazzard | $649,190 | -43% | 363 | -74 | $1,788 | $7,458,039 | 3 | Warner Bros. | false | false |
| 9 | 6 | Crash | $623,691 | -18.3% | 237 | -37 | $2,631 | $9,049,739 | 5 | Pathé | false | false |
| 10 | - | The Man | $605,921 | - | 240 | - | $2,524 | $605,921 | 1 | Entertainment Film Distributors | true | false |
| 11 | 5 | The Business | $525,999 | -46.2% | 273 | -6 | $1,926 | $2,106,386 | 2 | Pathé | false | false |
| 12 | 9 | The Adventures of Sharkboy and Lavagirl 3-D | $455,610 | -14.6% | 293 | -8 | $1,554 | $2,718,091 | 3 | Sony Pictures Releasing | false | false |
| 13 | 7 | Bewitched | $433,696 | -31.8% | 315 | -54 | $1,376 | $7,823,647 | 4 | Sony Pictures Releasing | false | false |
| 14 | - | Salaam Namaste | $380,944 | - | 35 | - | $10,884 | $380,944 | 1 | Yash Raj Films | true | false |
| 15 | 10 | The Cave | $177,232 | -62.8% | 162 | -114 | $1,094 | $2,985,547 | 3 | Entertainment Film Distributors | false | false |
| 16 | 12 | Madagascar | $158,902 | -28.5% | 230 | -73 | $690 | $41,353,856 | 9 | United International Pictures | false | false |
| 17 | 11 | The Island | $101,942 | -65.7% | 91 | -161 | $1,120 | $9,287,866 | 5 | Warner Bros. | false | false |
| 18 | 19 | Me and You and Everyone We Know | $96,264 | +36.2% | 25 | +4 | $3,850 | $704,625 | 4 | Optimum Releasing | false | false |
| 19 | - | The Aristocrats | $88,164 | - | 37 | - | $2,382 | $88,164 | 1 | Pathé | true | false |
| 20 | 13 | Wedding Crashers | $66,483 | -51.2% | 55 | -61 | $1,208 | $24,147,777 | 9 | Entertainment Film Distributors | false | false |
