| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | The Island | $172,088 | -23.2% | - | - | - | $465,411 | 2 | Warner Bros. | false | false |
| 2 | 4 | The Longest Yard | $103,176 | -40.6% | - | - | - | $1,145,917 | 4 | Sony Pictures Releasing | false | false |
| 3 | 2 | Fantastic Four | $94,142 | -62.3% | - | - | - | $1,516,443 | 4 | 20th Century Fox International | false | false |
| 4 | 6 | War of the Worlds | $87,028 | -46.3% | - | - | - | $2,370,061 | 5 | United International Pictures | false | false |
| 5 | 1 | Madagascar | $67,903 | -77.4% | - | - | - | $3,291,914 | 6 | United International Pictures | false | false |
| 6 | 5 | Herbie Fully Loaded | $38,793 | -77.6% | - | - | - | $871,130 | 5 | Buena Vista International | false | false |
| 7 | 13 | Ladies in Lavender | $37,282 | +5.7% | - | - | - | $901,207 | 9 | Icon Film Distribution | false | false |
| 8 | 10 | Mr. & Mrs. Smith | $37,094 | -26.2% | - | - | - | $2,385,843 | 8 | 20th Century Fox International | false | false |
| 9 | 9 | House of Wax | $36,371 | -42.5% | - | - | - | $274,927 | 3 | Roadshow Films | false | false |
| 10 | 11 | A Good Woman | $35,811 | -23.3% | - | - | - | $369,470 | 5 | Hopscotch Films | false | false |
| 11 | 14 | The Machinist | $35,297 | +3.9% | - | - | - | $83,432 | 2 | Rialto Distribution | false | false |
| 12 | 7 | Are We There Yet? | $31,906 | -71.7% | - | - | - | $420,068 | 3 | Sony Pictures Releasing | false | false |
| 13 | 12 | Batman Begins | $28,653 | -36.6% | - | - | - | $1,559,382 | 7 | Warner Bros. | false | false |
| 14 | 17 | Luther | $15,499 | +10.4% | - | - | - | $43,575 | 2 | - | false | false |
| 15 | 16 | Star Wars: Episode III - Revenge of the Sith | $13,748 | -6.1% | - | - | - | $3,936,277 | 11 | 20th Century Fox International | false | false |
| 16 | 8 | Pooh's Heffalump Movie | $13,297 | -80.4% | - | - | - | $331,978 | 4 | Buena Vista International | false | false |
| 17 | 20 | What the #$*! Do We (K)now!? 2005 Re-release | $9,316 | +9.8% | - | - | - | $121,773 | 11 | Hopscotch Films | false | false |
| 18 | 19 | Hotel Rwanda | $8,673 | -21.3% | - | - | - | $179,935 | 7 | Roadshow Films | false | false |
| 19 | - | The Sea Inside | $8,214 | - | - | - | - | $8,214 | 1 | Roadshow Films | true | false |
| 20 | 15 | The Sisterhood of the Traveling Pants | $8,137 | -61.3% | - | - | - | $147,670 | 4 | Warner Bros. | false | false |
