| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Monster-in-Law | $1,860,737 | - | - | - | - | $1,862,233 | 1 | Roadshow Films | true | false |
| 2 | 1 | Fantastic Four | $851,556 | -49.5% | - | - | - | $7,236,215 | 3 | 20th Century Fox International | false | false |
| 3 | 3 | Sin City | $838,172 | -42.2% | - | - | - | $3,045,152 | 2 | Buena Vista International | false | false |
| 4 | 2 | War of the Worlds | $828,971 | -44.5% | - | - | - | $14,561,602 | 4 | United International Pictures | false | false |
| 5 | 4 | Bewitched | $595,316 | -58.1% | - | - | - | $6,404,422 | 3 | Sony Pictures Releasing | false | false |
| 6 | - | Flight of the Phoenix | $337,843 | - | - | - | - | $343,259 | 1 | 20th Century Fox International | true | false |
| 7 | 5 | Madagascar | $287,810 | -63.8% | - | - | - | $18,955,787 | 6 | United International Pictures | false | false |
| 8 | 7 | House of Wax | $285,035 | -50.9% | - | - | - | $1,068,576 | 2 | Roadshow Films | false | false |
| 9 | 8 | Batman Begins | $256,474 | -50.2% | - | - | - | $11,515,080 | 6 | Warner Bros. | false | false |
| 10 | 6 | Herbie Fully Loaded | $195,448 | -69.4% | - | - | - | $6,950,833 | 5 | Buena Vista International | false | false |
| 11 | 9 | Mr. & Mrs. Smith | $149,608 | -51% | - | - | - | $15,251,734 | 7 | 20th Century Fox International | false | false |
| 12 | 11 | Oyster Farmer | $141,105 | -5.2% | - | - | - | $810,028 | 4 | Dendy Films | false | false |
| 13 | 12 | A Good Woman | $87,650 | -39.5% | - | - | - | $1,457,227 | 5 | Hopscotch Films | false | false |
| 14 | 10 | Pooh's Heffalump Movie | $66,571 | -64.6% | - | - | - | $1,494,958 | 5 | Buena Vista International | false | false |
| 15 | 14 | Star Wars: Episode III - Revenge of the Sith | $45,202 | -47.3% | - | - | - | $26,962,306 | 10 | 20th Century Fox International | false | false |
| 16 | 13 | The Sisterhood of the Traveling Pants | $28,019 | -76.8% | - | - | - | $1,339,503 | 5 | Warner Bros. | false | false |
| 17 | - | Ladies in Lavender | $26,511 | - | - | - | - | $2,626,712 | 18 | Icon Film Distribution | false | false |
| 18 | 16 | Sharks 3D | $26,210 | -39.2% | - | - | - | $521,443 | 12 | IMAX | false | false |
| 19 | - | What the #$*! Do We (K)now!? 2005 Re-release | $23,606 | - | - | - | - | $826,907 | 15 | Hopscotch Films | false | false |
| 20 | - | Downfall | $20,391 | - | - | - | - | $1,665,629 | 14 | Hopscotch Films | false | false |
