| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Madagascar | $3,556,478 | - | 480 | - | $7,409 | $3,556,478 | 1 | United International Pictures | true | false |
| 2 | - | Batman Begins | $2,464,801 | - | 453 | - | $5,441 | $2,464,801 | 1 | Warner Bros. | true | false |
| 3 | 1 | Star Wars: Episode III - Revenge of the Sith | $631,585 | -48.8% | 429 | -67 | $1,472 | $21,049,544 | 5 | 20th Century Fox International | false | false |
| 4 | 3 | Saint Ange | $294,636 | -42.3% | 153 | +1 | $1,925 | $956,097 | 2 | Vértigo Films | false | false |
| 5 | 2 | Unleashed | $259,209 | -55.4% | 243 | -9 | $1,066 | $2,131,097 | 3 | New World Pictures | false | false |
| 6 | 5 | Kingdom of Heaven | $191,342 | -51.8% | 273 | -84 | $700 | $13,866,338 | 7 | 20th Century Fox International | false | false |
| 7 | 7 | It's Not You, It's Me | $180,169 | -33.1% | 98 | -2 | $1,838 | $1,565,760 | 4 | Notro Films | false | false |
| 8 | 6 | Tapas | $166,885 | -40% | 182 | -19 | $916 | $3,588,557 | 6 | Filmax | false | false |
| 9 | - | A Different Loyalty | $161,368 | - | 93 | - | $1,735 | $161,368 | 1 | Manga Entertainment | true | false |
| 10 | 4 | Kung Fu Hustle | $151,913 | -61.7% | 201 | -1 | $755 | $1,354,462 | 3 | Sony Pictures Releasing | false | false |
| 11 | 9 | A Good Woman | $146,288 | -44% | 81 | - | $1,806 | $513,089 | 2 | Sony Pictures Releasing | false | false |
| 12 | 8 | Un rey en La Habana | $99,190 | -62.7% | 192 | -70 | $516 | $1,675,029 | 4 | Sony Pictures Releasing | false | false |
| 13 | 10 | The Interpreter | $69,479 | -57.2% | 102 | -46 | $681 | $7,566,455 | 10 | United International Pictures | false | false |
| 14 | - | Strayed | $57,305 | - | 25 | - | $2,292 | $57,305 | 1 | Vértigo Films | true | false |
| 15 | 11 | 20 Centimeters | $57,147 | -60.5% | 131 | -5 | $436 | $262,108 | 2 | - | false | false |
| 16 | 12 | 11:14 | $42,760 | -56.7% | 73 | -7 | $585 | $630,030 | 4 | Filmax | false | false |
| 17 | - | Pasos | $38,132 | - | 26 | - | $1,466 | $38,132 | 1 | Alta Films | true | false |
| 18 | 19 | Morir en San Hilario | $35,935 | -23.3% | 17 | -4 | $2,113 | $185,757 | 3 | Filmax | false | false |
| 19 | 18 | Primer | $31,967 | -45% | 30 | - | $1,065 | $120,676 | 2 | Notro Films | false | false |
| 20 | 14 | Rottweiler | $31,474 | -63.8% | 22 | -34 | $1,430 | $148,698 | 2 | Filmax | false | false |
