| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Star Wars: Episode III - Revenge of the Sith | $597,753 | -21.8% | 115 | - | $5,197 | $3,515,869 | 3 | 20th Century Fox International | false | false |
| 2 | - | Sin City | $287,274 | - | 83 | - | $3,461 | $342,322 | 1 | RCV Film Distribution | true | false |
| 3 | - | A Lot Like Love | $210,055 | - | 45 | - | $4,667 | $245,125 | 1 | Buena Vista International | true | false |
| 4 | 2 | Kingdom of Heaven | $147,365 | -3.6% | 99 | -5 | $1,488 | $2,612,405 | 5 | 20th Century Fox International | false | false |
| 5 | 3 | Hostage | $142,913 | +3.3% | 63 | - | $2,268 | $373,646 | 2 | Independent Films | false | false |
| 6 | 4 | House of Wax | $104,267 | -6.9% | 40 | - | $2,606 | $258,050 | 2 | Warner Bros. | false | false |
| 7 | 5 | The Pacifier | $91,995 | -10% | 67 | -1 | $1,373 | $2,041,234 | 6 | Buena Vista International | false | false |
| 8 | 6 | The Wedding Date | $54,834 | -13.6% | 50 | - | $1,096 | $545,557 | 4 | N/A | false | false |
| 9 | 9 | Pooh's Heffalump Movie | $44,637 | +221.2% | 86 | - | $519 | $584,441 | 6 | Buena Vista International | false | false |
| 10 | 10 | Robots | $40,277 | +190.1% | 97 | -13 | $415 | $1,642,805 | 11 | 20th Century Fox International | false | false |
| 11 | 7 | The Interpreter | $34,584 | -22.6% | 37 | -18 | $934 | $1,367,546 | 8 | United International Pictures | false | false |
| 12 | - | A Love Song for Bobby Long | $22,532 | - | 20 | - | $1,126 | $42,795 | 1 | Moonlight Films | true | false |
| 13 | 8 | Hitch | $16,234 | -11.6% | 19 | -19 | $854 | $3,837,042 | 13 | United International Pictures | false | false |
| 14 | 12 | The Consequences of Love | $16,144 | +61.5% | 12 | - | $1,345 | $98,834 | 4 | Cinemien | false | false |
| 15 | 13 | What the #$*! Do We (K)now!? 2005 Re-release | $11,063 | +13.1% | 8 | - | $1,382 | $84,261 | 4 | Cinemien | false | false |
| 16 | 11 | Dear Wendy | $9,735 | -5.7% | 14 | - | $695 | $56,763 | 3 | A-Film Distribution | false | false |
| 17 | 14 | The Assassination of Richard Nixon | $9,643 | -1.4% | 12 | - | $803 | $97,864 | 4 | Independent Films | false | false |
| 18 | 18 | The Sea Inside | $6,998 | +71.9% | 19 | +1 | $368 | $584,883 | 19 | A-Film Distribution | false | false |
| 19 | 20 | Nobody Knows | $5,491 | +56.5% | 8 | -1 | $686 | $101,087 | 8 | Bright Angel Distribution | false | false |
| 20 | - | Sideways | $5,016 | - | 6 | - | $836 | $570,873 | 16 | 20th Century Fox International | false | false |
