| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Godzilla vs. Kong | - | - | - | $90,128,538 | 3,084 | $100,916,094 | Mar 31 | Warner Bros. | false |
| 2 | Raya and the Last Dragon | - | - | - | $41,951,907 | 2,375 | $54,723,032 | Mar 5 | Walt Disney Studios Motion Pictures | false |
| 3 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | - | - | - | $36,585,941 | 2,087 | $49,505,008 | Apr 23 | FUNimation Entertainment | false |
| 4 | Mortal Kombat | - | - | - | $30,918,764 | 3,114 | $42,326,031 | Apr 23 | Warner Bros. | false |
| 5 | Tom & Jerry | - | - | - | $27,838,804 | 2,563 | $46,536,687 | Feb 26 | Warner Bros. | false |
| 6 | Nobody | - | - | - | $23,807,180 | 2,567 | $27,568,035 | Mar 26 | Universal Pictures | false |
| 7 | The Unholy | - | - | - | $13,444,753 | 2,057 | $15,532,137 | Apr 2 | Screen Gems | false |
| 8 | Chaos Walking | - | - | - | $13,248,156 | 2,132 | $13,287,908 | Mar 5 | Lionsgate | false |
| 9 | The Courier | - | - | - | $6,291,133 | 1,641 | $6,613,432 | Mar 19 | Roadside Attractions | false |
| 10 | The Croods: A New Age | - | - | - | $4,798,235 | 2,211 | $58,568,815 | Nov 25 | Universal Pictures | false |
| 11 | Boogie | - | - | - | $4,178,620 | 1,272 | $4,178,620 | Mar 5 | Focus Features | false |
| 12 | Voyagers | - | - | - | $3,113,540 | 1,996 | $3,149,935 | Apr 9 | Lionsgate | false |
| 13 | The Marksman | - | - | - | $3,063,584 | 2,018 | $15,566,093 | Jan 15 | Open Road Films (II) | false |
| 14 | The Girl Who Believes in Miracles | - | - | - | $2,818,725 | 1,012 | $3,163,362 | Apr 2 | Atlas Distribution Company | false |
| 15 | Wonder Woman 1984 | - | - | - | $2,545,561 | 2,218 | $46,801,036 | Dec 25 | Warner Bros. | false |
| 16 | Separation | - | - | - | $2,303,873 | 1,911 | $4,509,143 | Apr 30 | Open Road Films (II) | false |
| 17 | Minari | - | - | - | $2,244,307 | 912 | $3,110,580 | Feb 12 | A24 | false |
| 18 | The Little Things | - | - | - | $2,105,575 | 2,206 | $15,342,746 | Jan 29 | Warner Bros. | false |
| 19 | The Father | - | - | - | $1,689,738 | 933 | $2,122,771 | Feb 26 | Sony Pictures Classics | false |
| 20 | Judas and the Black Messiah | - | - | - | $1,252,706 | 1,906 | $5,478,009 | Feb 12 | Warner Bros. | false |
| 21 | Promising Young Woman | - | - | - | $1,172,435 | 1,448 | $6,460,965 | Dec 25 | Focus Features | false |
| 22 | Together Together | - | - | - | $1,134,989 | 665 | $1,437,938 | Apr 23 | Bleecker Street Media | false |
| 23 | In the Earth | - | - | - | $1,070,607 | 571 | $1,113,723 | Apr 16 | Neon | false |
| 24 | Scott Pilgrim vs. the World 10th Anniversary (2021 Re-release) | - | - | - | $1,035,830 | 448 | $1,867,625 | - | Universal Pictures | false |
| 25 | Monster Hunter | - | - | - | $1,009,680 | 1,817 | $15,162,470 | Dec 18 | Screen Gems | false |
| 26 | Wrong Turn | - | - | - | $844,907 | 259 | $1,251,184 | Jan 26 | Saban Films | false |
| 27 | Lamb of God: The Concert Film | - | - | - | $744,513 | 138 | $744,813 | Mar 12 | Excel Entertainment | false |
| 28 | French Exit | - | - | - | $663,727 | 493 | $741,895 | Feb 12 | Sony Pictures Classics | false |
| 29 | The War with Grandpa | - | - | - | $655,604 | 2,365 | $21,277,892 | Oct 9 | 101 Studios | false |
| 30 | News of the World | - | - | - | $633,480 | 1,986 | $12,668,325 | Dec 25 | Universal Pictures | false |
| 31 | City of Lies | - | - | - | $572,493 | 502 | $572,493 | Mar 19 | Saban Films | false |
| 32 | Nomadland | - | - | - | $549,000 | 1,200 | $3,700,000 | Feb 19 | Searchlight Pictures | false |
| 33 | Long Weekend | - | - | - | $530,693 | 821 | $1,018,532 | Mar 12 | Stage 6 Films | false |
| 34 | Jathi Ratnalu | - | - | - | $470,000 | 130 | $470,000 | Mar 12 | Flyhigh Cinemas | false |
| 35 | 2021 Oscar Nominated Short Films: Live Action | - | - | - | $439,169 | 184 | $443,050 | Apr 2 | Magnolia Pictures | false |
| 36 | Dutch | - | - | - | $404,371 | 202 | $404,371 | Mar 12 | Faith Media Distribution | false |
| 37 | Four Good Days | - | - | - | $401,517 | 489 | $837,849 | Apr 30 | Vertical Entertainment | false |
| 38 | Land | - | - | - | $366,935 | 1,349 | $2,577,830 | Feb 12 | Focus Features | false |
| 39 | The Mauritanian | - | - | - | $266,749 | 287 | $836,536 | Feb 12 | STX Entertainment | false |
| 40 | Tenet | - | - | - | $260,683 | 2,930 | $58,504,105 | Sep 3 | Warner Bros. | false |
| 41 | The Truffle Hunters | - | - | - | $159,889 | 105 | $521,202 | Mar 5 | Sony Pictures Classics | false |
| 42 | SAS: Rise of the Black Swan | - | - | - | $146,329 | 189 | $146,329 | Apr 16 | Vertical Entertainment | false |
| 43 | Crisis | - | - | - | $145,535 | 216 | $404,738 | Feb 26 | Quiver Distribution | false |
| 44 | Held | - | - | - | $129,898 | 129 | $142,817 | Apr 9 | Magnolia Pictures | false |
| 45 | Six Minutes to Midnight | - | - | - | $129,572 | 145 | $132,500 | Mar 26 | IFC Films | false |
| 46 | Limbo | - | - | - | $121,325 | 213 | $224,405 | Apr 30 | Focus Features | false |
| 47 | The Resort | - | - | - | $111,571 | 114 | $191,996 | Apr 30 | Vertical Entertainment | false |
| 48 | Shiva Baby | - | - | - | $93,188 | 27 | $159,294 | Apr 2 | Utopia | false |
| 49 | Willy's Wonderland | - | - | - | $90,606 | 171 | $418,286 | Feb 12 | Screen Media Films | false |
| 50 | Cliff Walkers | - | - | - | $78,751 | 65 | $152,972 | Apr 30 | CMC Pictures | false |
| 51 | Blithe Spirit | - | - | - | $71,033 | 239 | $282,500 | Feb 19 | IFC Films | false |
| 52 | 100% Wolf | - | - | - | $70,301 | 124 | $658,764 | Oct 9 | Viva Pictures | false |
| 53 | Come True | - | - | - | $62,080 | 96 | $62,080 | Mar 12 | IFC Films | false |
| 54 | Son | - | - | - | $55,057 | 29 | $55,068 | Mar 5 | RLJ Entertainment | false |
| 55 | My Salinger Year | - | - | - | $54,730 | 123 | $54,730 | Mar 5 | IFC Films | false |
| 56 | Last Call | - | - | - | $48,144 | 110 | $48,144 | Mar 19 | IFC Films | false |
| 57 | Safer at Home | - | - | - | $44,542 | 79 | $95,643 | Feb 26 | Vertical Entertainment | false |
| 58 | Gunda | - | - | - | $35,416 | 35 | $115,691 | Apr 16 | Neon | false |
| 59 | A Writer's Odyssey | - | - | - | $33,405 | 117 | $160,013 | Feb 12 | CMC Pictures | false |
| 60 | Fatale | - | - | - | $32,385 | 1,222 | $6,306,897 | Dec 18 | Lionsgate | false |
| 61 | Monday | - | - | - | $30,932 | 54 | $30,932 | Apr 16 | IFC Films | false |
| 62 | Trigger Point | - | - | - | $29,262 | 77 | $29,262 | Apr 16 | Screen Media Films | false |
| 63 | Honeydew | - | - | - | $27,825 | 14 | $32,890 | Mar 12 | Dark Star Pictures | false |
| 64 | Jakob's Wife | - | - | - | $27,588 | 101 | $27,588 | Apr 16 | RLJ Entertainment | false |
| 65 | Senior Moment | - | - | - | $26,456 | 57 | $41,598 | Mar 26 | Screen Media Films | false |
| 66 | Moffie | - | - | - | $24,520 | 51 | $24,520 | Apr 9 | IFC Films | false |
| 67 | The Vigil | - | - | - | $19,656 | 55 | $50,439 | Feb 26 | IFC Films | false |
| 68 | Mystery of the Kingdom of God | - | - | - | $17,316 | 106 | $17,316 | Mar 26 | Atlas Distribution Company | false |
| 69 | Counter Column | - | - | - | $16,797 | 7 | $32,323 | Oct 16 | Not That Kind of Movie Productions | false |
| 70 | About Endlessness | - | - | - | $16,018 | 17 | $51,386 | Apr 30 | Magnolia Pictures | false |
| 71 | We Broke Up | - | - | - | $15,063 | 35 | $15,063 | Apr 16 | Vertical Entertainment | false |
| 72 | Stray | - | - | - | $12,145 | 17 | $13,325 | Mar 5 | Magnolia Pictures | false |
| 73 | American Skin | - | - | - | $11,854 | 72 | $282,332 | Jan 15 | Vertical Entertainment | false |
| 74 | My Zoe | - | - | - | $9,114 | 237 | $52,733 | Feb 26 | Blue Fox Entertainment | false |
| 75 | Supernova | - | - | - | $7,802 | 330 | $234,220 | Jan 29 | Bleecker Street Media | false |
| 76 | The Boonies | - | - | - | $6,091 | 2 | $6,887 | Mar 31 | Indican Pictures | false |
| 77 | Dark State | - | - | - | $5,824 | 7 | $5,824 | Mar 19 | Atlas Distribution Company | false |
| 78 | Blood Brothers: Civil War | - | - | - | $5,191 | 2 | $5,191 | Apr 2 | Indican Pictures | false |
| 79 | Bill Traylor: Chasing Ghosts | - | - | - | $4,504 | 2 | $4,504 | Apr 16 | Kino Lorber | false |
| 80 | The World to Come | - | - | - | $4,406 | 277 | $116,143 | Feb 12 | Bleecker Street Media | false |
| 81 | No Place | - | - | - | $4,194 | 1 | $4,194 | Mar 5 | Indican Pictures | false |
| 82 | Endless Rain | - | - | - | $4,045 | 14 | $7,334 | Apr 30 | Sony Pictures Releasing | false |
| 83 | Dara of Jasenovac | - | - | - | $3,250 | 23 | $52,786 | Feb 5 | 101 Studios | false |
| 84 | Slalom | - | - | - | $2,796 | 4 | $2,788 | Apr 9 | Kino Lorber | false |
| 85 | Abandoned: Angelique's Isle | - | - | - | $2,699 | 1 | $6,055 | Feb 19 | Indican Pictures | false |
| 86 | Things Don't Stay Fixed | - | - | - | $2,647 | 3 | $5,430 | Mar 26 | Indican Pictures | false |
| 87 | The Incredible 25th Year of Mitzi Bearclaw | - | - | - | $2,569 | 2 | $12,486 | Feb 12 | Indican Pictures | false |
| 88 | The Shade Shepherd | - | - | - | $2,293 | 1 | $4,409 | Oct 16 | Indican Pictures | false |
| 89 | Bang! Bang! | - | - | - | $1,348 | 1 | $6,390 | Oct 23 | Indican Pictures | false |
| 90 | First Signal | - | - | - | $750 | 1 | $880 | Mar 26 | The Ashton Times | false |
| 91 | Little Fish | - | - | - | $508 | 84 | $39,053 | Feb 5 | IFC Films | false |
