| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Beetlejuice | - | - | - | $47,864,747 | 1,582 | $73,707,461 | Mar 30 | Warner Bros. | false |
| 2 | Good Morning, Vietnam | - | - | - | $35,415,438 | 1,598 | $123,922,370 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 3 | Biloxi Blues | - | - | - | $34,709,210 | 1,330 | $43,184,798 | Mar 25 | Universal Pictures | false |
| 4 | Moonstruck | - | - | - | $27,230,802 | 1,178 | $80,640,528 | Dec 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 5 | The Fox and the Hound 1988 Re-release | - | - | - | $23,556,988 | 1,567 | $23,556,988 | Mar 25 | Walt Disney Studios Motion Pictures | false |
| 6 | Colors | - | - | - | $21,088,943 | 1,388 | $46,616,067 | Apr 15 | Orion Pictures | false |
| 7 | Police Academy 5: Assignment: Miami Beach | - | - | - | $19,510,371 | 1,700 | $19,510,371 | Mar 18 | Warner Bros. | false |
| 8 | The Last Emperor | - | - | - | $18,047,287 | 877 | $43,984,230 | Nov 20 | Columbia Pictures | false |
| 9 | Johnny Be Good | - | - | - | $17,550,399 | 1,194 | $17,550,399 | Mar 25 | Orion Pictures | false |
| 10 | The Seventh Sign | - | - | - | $16,684,164 | 1,258 | $18,875,011 | Apr 1 | TriStar Pictures | false |
| 11 | Bright Lights, Big City | - | - | - | $16,118,077 | 1,199 | $16,118,077 | Apr 1 | United Artists | false |
| 12 | Three Men and a Baby | - | - | - | $15,856,915 | 1,813 | $167,780,960 | Nov 25 | Walt Disney Studios Motion Pictures | false |
| 13 | Masquerade | - | - | - | $15,855,828 | 1,031 | $15,855,828 | Mar 11 | Metro-Goldwyn-Mayer (MGM) | false |
| 14 | Vice Versa | - | - | - | $13,664,060 | 1,225 | $13,664,060 | Mar 11 | Columbia Pictures | false |
| 15 | D.O.A. | - | - | - | $12,706,478 | 908 | $12,706,478 | Mar 18 | Walt Disney Studios Motion Pictures | false |
| 16 | Above the Law | - | - | - | $12,527,247 | 868 | $18,869,631 | Apr 8 | Warner Bros. | false |
| 17 | Frantic | - | - | - | $11,884,267 | 1,101 | $17,637,950 | Feb 26 | Warner Bros. | false |
| 18 | Shoot to Kill | - | - | - | $11,188,810 | 1,519 | $29,300,090 | Feb 12 | Walt Disney Studios Motion Pictures | false |
| 19 | Bloodsport | - | - | - | $11,115,595 | 124 | $11,806,119 | Feb 26 | Cannon Film Distributors | false |
| 20 | Moving | - | - | - | $10,815,378 | 1,404 | $10,815,378 | Mar 4 | Warner Bros. | false |
| 21 | Bad Dreams | - | - | - | $9,797,098 | 1,185 | $9,797,098 | Apr 8 | Twentieth Century Fox | false |
| 22 | School Daze | - | - | - | $9,399,814 | 224 | $14,545,844 | Feb 12 | Columbia Pictures | false |
| 23 | Switching Channels | - | - | - | $9,129,999 | 971 | $9,129,999 | Mar 4 | TriStar Pictures | false |
| 24 | Return to Snowy River | - | - | - | $8,658,946 | 1,121 | $13,687,027 | Apr 15 | Walt Disney Studios Motion Pictures | false |
| 25 | The Unbearable Lightness of Being | - | - | - | $8,271,308 | 140 | $10,006,806 | Feb 5 | Orion Pictures | false |
| 26 | Stand and Deliver | - | - | - | $8,123,482 | 472 | $13,994,920 | Mar 11 | Warner Bros. | false |
| 27 | Casual Sex? | - | - | - | $8,048,151 | 1,265 | $12,277,096 | Apr 22 | Universal Pictures | false |
| 28 | A New Life | - | - | - | $7,721,852 | 796 | $7,721,852 | Mar 25 | Paramount Pictures | false |
| 29 | Off Limits | - | - | - | $7,242,035 | 1,371 | $7,242,035 | Mar 11 | Twentieth Century Fox | false |
| 30 | The Milagro Beanfield War | - | - | - | $7,012,749 | 437 | $13,825,794 | Mar 18 | Universal Pictures | false |
| 31 | Action Jackson | - | - | - | $6,019,847 | 1,249 | $20,256,975 | Feb 12 | Lorimar Motion Pictures | false |
| 32 | Hairspray | - | - | - | $5,862,498 | 227 | $6,671,108 | Feb 26 | New Line Cinema | false |
| 33 | Fatal Attraction | - | - | - | $5,612,019 | 1,401 | $156,645,693 | Sep 18 | Paramount Pictures | false |
| 34 | Broadcast News | - | - | - | $5,231,703 | 848 | $51,249,404 | Dec 18 | Twentieth Century Fox | false |
| 35 | The Unholy | - | - | - | $5,031,465 | 1,189 | $6,337,299 | Apr 22 | Vestron Pictures | false |
| 36 | She's Having a Baby | - | - | - | $3,225,255 | 1,133 | $16,031,707 | Feb 5 | Paramount Pictures | false |
| 37 | A Night in the Life of Jimmy Reardon | - | - | - | $3,016,740 | 882 | $6,264,058 | Feb 26 | Twentieth Century Fox | false |
| 38 | Hope and Glory | - | - | - | $2,755,282 | 328 | $10,021,120 | Oct 16 | Columbia Pictures | false |
| 39 | The Serpent and the Rainbow | - | - | - | $2,661,685 | 1,431 | $19,595,031 | Feb 5 | Universal Pictures | false |
| 40 | 18 Again! | - | - | - | $2,567,099 | 1,152 | $2,567,099 | Apr 8 | New World Pictures | false |
| 41 | Sunset | - | - | - | $2,558,011 | 1,024 | $4,594,452 | Apr 29 | TriStar Pictures | false |
| 42 | Critters 2: The Main Course | - | - | - | $2,248,216 | 1,114 | $3,813,293 | Apr 29 | New Line Cinema | false |
| 43 | Little Nikita | - | - | - | $1,733,070 | 376 | $1,733,070 | Mar 18 | Columbia Pictures | false |
| 44 | Satisfaction | - | - | - | $1,665,079 | 1,018 | $8,253,123 | Feb 12 | Twentieth Century Fox | false |
| 45 | Ironweed | - | - | - | $1,296,715 | 600 | $7,393,346 | Dec 18 | TriStar Pictures | false |
| 46 | Sammy and Rosie Get Laid | - | - | - | $1,141,028 | 15 | $1,196,336 | Oct 30 | Cinecom Pictures | false |
| 47 | A Time of Destiny | - | - | - | $986,820 | 220 | $1,212,487 | Apr 22 | Columbia Pictures | false |
| 48 | Appointment with Death | - | - | - | $960,040 | 465 | $960,040 | Apr 15 | Cannon Film Distributors | false |
| 49 | Two Moon Junction | - | - | - | $788,202 | 458 | $1,547,397 | Apr 29 | Lorimar Motion Pictures | false |
| 50 | And God Created Woman | - | - | - | $717,376 | 385 | $717,376 | Mar 4 | Vestron Pictures | false |
| 51 | Dominick and Eugene | - | - | - | $402,065 | 76 | $3,076,031 | Mar 18 | Orion Pictures | false |
| 52 | Lady in White | - | - | - | $358,029 | 107 | $1,705,139 | Apr 22 | New Century | false |
| 53 | Plain Clothes | - | - | - | $289,323 | 193 | $289,323 | Apr 15 | Paramount Pictures | false |
| 54 | Mondo New York | - | - | - | $193,209 | 1 | $193,209 | Apr 22 | Fourth and Broadway | false |
| 55 | Stormy Monday | - | - | - | $61,830 | 49 | $1,791,328 | Apr 22 | Atlantic Releasing Corporation | false |
| 56 | White Mischief | - | - | - | $47,637 | 87 | $3,107,551 | Apr 22 | Columbia Pictures | false |
| 57 | Powaqqatsi | - | - | - | $41,199 | 22 | $589,244 | Apr 29 | Cannon Film Distributors | false |
| 58 | The Lighthorsemen | - | - | - | $33,779 | 16 | $33,779 | Apr 8 | Cinecom Pictures | false |
| 59 | The Moderns | - | - | - | $33,235 | 28 | $2,011,497 | Apr 15 | Alive Films | false |
| 60 | Wings of Desire | - | - | - | $30,639 | 29 | $3,210,139 | Apr 29 | Orion Classics | false |
| 61 | Bellman and True | - | - | - | $30,423 | 8 | $226,944 | Apr 1 | Island Pictures | false |
| 62 | Consuming Passions | - | - | - | $22,512 | 5 | $118,206 | Apr 6 | The Samuel Goldwyn Company | false |
| 63 | Beatrice | - | - | - | $17,838 | 8 | $211,821 | Mar 18 | The Samuel Goldwyn Company | false |
| 64 | Da | - | - | - | $17,454 | 1 | $644,532 | Apr 29 | FilmDallas Pictures | false |
| 65 | Aria | - | - | - | $10,574 | 34 | $1,028,679 | Mar 18 | Miramax | false |
| 66 | When the Wind Blows | - | - | - | $5,274 | 1 | $5,274 | Mar 11 | Kings Road Entertainment | false |
