| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Home Alone | - | - | - | $156,070,787 | 2,173 | $285,761,243 | Nov 16 | Twentieth Century Fox | false |
| 2 | Dances with Wolves | - | - | - | $63,818,711 | 1,636 | $184,208,848 | Nov 9 | Orion Pictures | false |
| 3 | Three Men and a Little Lady | - | - | - | $55,181,094 | 1,614 | $71,609,321 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 4 | Misery | - | - | - | $41,027,722 | 1,370 | $61,276,872 | Nov 30 | Columbia Pictures | false |
| 5 | Rocky V | - | - | - | $40,946,358 | 2,106 | $40,946,358 | Nov 16 | United Artists | false |
| 6 | The Godfather Part III | - | - | - | $36,447,884 | 1,922 | $66,666,062 | Dec 25 | Paramount Pictures | false |
| 7 | Kindergarten Cop | - | - | - | $35,328,075 | 1,937 | $91,457,688 | Dec 22 | Universal Pictures | false |
| 8 | Predator 2 | - | - | - | $30,669,413 | 1,978 | $30,669,413 | Nov 21 | Twentieth Century Fox | false |
| 9 | Look Who's Talking Too | - | - | - | $29,341,936 | 1,647 | $47,789,074 | Dec 14 | TriStar Pictures | false |
| 10 | Ghost | - | - | - | $29,224,273 | 1,766 | $217,631,306 | Jul 13 | Paramount Pictures | false |
| 11 | Edward Scissorhands | - | - | - | $28,685,165 | 1,372 | $56,362,352 | Dec 7 | Twentieth Century Fox | false |
| 12 | Child's Play 2 | - | - | - | $28,501,605 | 2,017 | $28,501,605 | Nov 9 | Universal Pictures | false |
| 13 | Jacob's Ladder | - | - | - | $26,118,851 | 1,264 | $26,118,851 | Nov 2 | TriStar Pictures | false |
| 14 | The Rescuers Down Under | - | - | - | $22,330,340 | 1,487 | $27,931,461 | Nov 16 | Walt Disney Studios Motion Pictures | false |
| 15 | The Rookie | - | - | - | $18,306,082 | 1,862 | $21,633,874 | Dec 7 | Warner Bros. | false |
| 16 | Mermaids | - | - | - | $17,527,278 | 1,154 | $35,419,397 | Dec 14 | Orion Pictures | false |
| 17 | Reversal of Fortune | - | - | - | $14,448,649 | 661 | $15,445,131 | Oct 19 | Warner Bros. | false |
| 18 | Quigley Down Under | - | - | - | $12,786,015 | 1,094 | $21,413,105 | Oct 19 | Metro-Goldwyn-Mayer (MGM) | false |
| 19 | Sibling Rivalry | - | - | - | $12,678,670 | 1,455 | $17,854,933 | Oct 26 | Columbia Pictures | false |
| 20 | The Russia House | - | - | - | $12,409,859 | 768 | $22,997,992 | Dec 22 | Metro-Goldwyn-Mayer (MGM) | false |
| 21 | The Bonfire of the Vanities | - | - | - | $11,494,968 | 1,395 | $15,691,192 | Dec 22 | Warner Bros. | false |
| 22 | White Palace | - | - | - | $11,423,925 | 892 | $17,487,531 | Oct 19 | Universal Pictures | false |
| 23 | Marked for Death | - | - | - | $11,111,637 | 1,974 | $46,044,396 | Oct 5 | Twentieth Century Fox | false |
| 24 | Memphis Belle | - | - | - | $10,939,594 | 1,368 | $27,441,977 | Oct 12 | Warner Bros. | false |
| 25 | Avalon | - | - | - | $8,641,902 | 635 | $15,740,796 | Oct 5 | TriStar Pictures | false |
| 26 | Havana | - | - | - | $7,443,104 | 835 | $9,243,140 | Dec 14 | Universal Pictures | false |
| 27 | Fantasia 1990 Re-release | - | - | - | $6,967,631 | 481 | $25,363,371 | Oct 5 | Walt Disney Studios Motion Pictures | false |
| 28 | Mr. Destiny | - | - | - | $5,669,168 | 1,025 | $15,379,253 | Oct 12 | Walt Disney Studios Motion Pictures | false |
| 29 | Almost an Angel | - | - | - | $5,125,360 | 1,373 | $6,939,946 | Dec 22 | Paramount Pictures | false |
| 30 | Graveyard Shift | - | - | - | $5,093,711 | 1,603 | $11,582,891 | Oct 26 | Paramount Pictures | false |
| 31 | Henry & June | - | - | - | $4,964,276 | 295 | $11,567,449 | Oct 5 | Universal Pictures | false |
| 32 | Graffiti Bridge | - | - | - | $4,562,778 | 688 | $4,562,778 | Nov 2 | Warner Bros. | false |
| 33 | Pacific Heights | - | - | - | $4,098,227 | 1,291 | $29,381,956 | Sep 28 | Twentieth Century Fox | false |
| 34 | Goodfellas | - | - | - | $3,484,274 | 1,328 | $46,836,214 | Sep 19 | Warner Bros. | false |
| 35 | The Krays | - | - | - | $2,060,847 | 392 | $2,060,847 | Nov 9 | Miramax | false |
| 36 | The Nutcracker Prince | - | - | - | $1,781,694 | 906 | $1,781,694 | Nov 21 | Warner Bros. | false |
| 37 | Tune in Tomorrow... | - | - | - | $1,707,366 | 207 | $1,794,001 | Oct 26 | Cinecom Pictures | false |
| 38 | Miller's Crossing | - | - | - | $1,311,947 | 289 | $5,080,409 | Sep 21 | Twentieth Century Fox | false |
| 39 | Robot Jox | - | - | - | $1,272,977 | 333 | $1,272,977 | Nov 21 | Triumph Releasing Corporation | false |
| 40 | Awakenings | - | - | - | $1,241,038 | 1,330 | $52,096,475 | Dec 22 | Columbia Pictures | false |
| 41 | To Sleep with Anger | - | - | - | $1,134,786 | 23 | $1,161,135 | Oct 12 | The Samuel Goldwyn Company | false |
| 42 | King of New York | - | - | - | $1,015,743 | 119 | $2,554,476 | Sep 28 | New Line Cinema | false |
| 43 | Waiting for the Light | - | - | - | $808,690 | 149 | $808,690 | Nov 2 | Triumph Releasing Corporation | false |
| 44 | Night of the Living Dead | - | - | - | $806,019 | 1,544 | $5,835,247 | Oct 19 | Columbia Pictures | false |
| 45 | C'est la vie | - | - | - | $805,472 | 28 | $805,472 | Nov 2 | The Samuel Goldwyn Company | false |
| 46 | The Return of Superfly | - | - | - | $610,402 | 260 | $610,402 | Nov 9 | Triton Pictures | false |
| 47 | Hamlet | - | - | - | $455,972 | 624 | $20,710,451 | Dec 22 | Warner Bros. | false |
| 48 | The Sheltering Sky | - | - | - | $414,202 | 95 | $2,075,084 | Dec 14 | Warner Bros. | false |
| 49 | The Hot Spot | - | - | - | $404,505 | 365 | $1,293,976 | Oct 12 | Orion Pictures | false |
| 50 | Frankenstein Unbound | - | - | - | $334,748 | 34 | $334,748 | Nov 2 | Twentieth Century Fox | false |
| 51 | Alice | - | - | - | $322,756 | 325 | $7,331,647 | Dec 25 | Orion Pictures | false |
| 52 | Green Card | - | - | - | $263,985 | 757 | $29,888,235 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 53 | Come See the Paradise | - | - | - | $222,286 | 97 | $947,306 | Dec 25 | Twentieth Century Fox | false |
| 54 | The Grifters | - | - | - | $103,832 | 780 | $13,446,769 | Dec 7 | Miramax | false |
| 55 | Mr. & Mrs. Bridge | - | - | - | $98,086 | 240 | $7,698,010 | Nov 23 | Miramax | false |
| 56 | The Field | - | - | - | $88,114 | 40 | $1,494,399 | Dec 22 | Avenue Pictures Productions | false |
| 57 | Hidden Agenda | - | - | - | $86,726 | 114 | $1,030,938 | Nov 21 | Hemdale | false |
| 58 | The Long Walk Home | - | - | - | $77,016 | 272 | $4,873,620 | Dec 22 | Miramax | false |
| 59 | Vincent & Theo | - | - | - | $36,247 | 59 | $2,231,274 | Nov 2 | Hemdale | false |
| 60 | Eating | - | - | - | $18,820 | 19 | $2,100,538 | Nov 16 | Rainbow Releasing | false |
| 61 | Just Ask for Diamond | - | - | - | $12,751 | 30 | $12,751 | Nov 30 | Castle Hill Productions | false |
