| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Three Men and a Baby | - | - | - | $86,606,579 | 1,813 | $167,780,960 | Nov 25 | Walt Disney Studios Motion Pictures | false |
| 2 | Fatal Attraction | - | - | - | $51,777,662 | 1,401 | $156,645,693 | Sep 18 | Paramount Pictures | false |
| 3 | Planes, Trains & Automobiles | - | - | - | $40,123,981 | 1,684 | $49,530,280 | Nov 25 | Paramount Pictures | false |
| 4 | Throw Momma from the Train | - | - | - | $39,026,073 | 1,623 | $57,915,972 | Dec 11 | Orion Pictures | false |
| 5 | The Running Man | - | - | - | $36,276,906 | 1,694 | $38,122,105 | Nov 13 | TriStar Pictures | false |
| 6 | Eddie Murphy: Raw | - | - | - | $35,204,043 | 1,494 | $50,504,655 | Dec 18 | Paramount Pictures | false |
| 7 | Cinderella 1987 Re-release | - | - | - | $30,633,626 | 1,657 | $34,101,149 | Nov 20 | Walt Disney Studios Motion Pictures | false |
| 8 | Nuts | - | - | - | $25,583,302 | 1,112 | $30,950,002 | Nov 20 | Warner Bros. | false |
| 9 | Wall Street | - | - | - | $23,825,172 | 989 | $43,848,069 | Dec 11 | Twentieth Century Fox | false |
| 10 | Hello Again | - | - | - | $20,419,446 | 1,207 | $20,419,446 | Nov 6 | Walt Disney Studios Motion Pictures | false |
| 11 | *batteries not included | - | - | - | $20,287,929 | 1,367 | $32,945,797 | Dec 18 | Universal Pictures | false |
| 12 | Broadcast News | - | - | - | $18,073,103 | 848 | $51,249,404 | Dec 18 | Twentieth Century Fox | false |
| 13 | Baby Boom | - | - | - | $17,095,102 | 892 | $26,712,476 | Oct 9 | United Artists | false |
| 14 | Flowers in the Attic | - | - | - | $15,151,736 | 1,095 | $15,151,736 | Nov 20 | New World Pictures | false |
| 15 | Overboard | - | - | - | $14,234,300 | 1,135 | $26,713,187 | Dec 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 16 | The Princess Bride | - | - | - | $13,840,798 | 803 | $30,857,814 | Sep 25 | Twentieth Century Fox | false |
| 17 | Dirty Dancing | - | - | - | $13,124,008 | 1,012 | $63,446,382 | Aug 21 | Vestron Pictures | false |
| 18 | Empire of the Sun | - | - | - | $12,752,003 | 673 | $22,238,696 | Dec 11 | Warner Bros. | false |
| 19 | Less Than Zero | - | - | - | $12,396,383 | 871 | $12,396,383 | Nov 6 | Twentieth Century Fox | false |
| 20 | Suspect | - | - | - | $8,540,286 | 1,029 | $18,782,400 | Oct 23 | TriStar Pictures | false |
| 21 | Fatal Beauty | - | - | - | $8,254,441 | 1,117 | $12,046,526 | Oct 30 | Metro-Goldwyn-Mayer (MGM) | false |
| 22 | Teen Wolf Too | - | - | - | $7,888,703 | 1,540 | $7,888,703 | Nov 20 | Atlantic Releasing Corporation | false |
| 23 | Like Father Like Son | - | - | - | $7,719,019 | 1,277 | $34,377,585 | Oct 2 | TriStar Pictures | false |
| 24 | Hiding Out | - | - | - | $7,019,441 | 988 | $7,019,441 | Nov 6 | De Laurentiis Entertainment Group (DEG) | false |
| 25 | Death Wish 4: The Crackdown | - | - | - | $6,880,310 | 1,030 | $6,880,310 | Nov 6 | Cannon Film Distributors | false |
| 26 | The Hidden | - | - | - | $6,254,564 | 1,045 | $9,747,988 | Oct 30 | New Line Cinema | false |
| 27 | The Last Emperor | - | - | - | $5,981,606 | 877 | $43,984,230 | Nov 20 | Columbia Pictures | false |
| 28 | Leonard Part 6 | - | - | - | $4,615,255 | 1,149 | $4,615,255 | Dec 18 | Columbia Pictures | false |
| 29 | Prince of Darkness | - | - | - | $4,606,482 | 1,239 | $14,182,492 | Oct 23 | Universal Pictures | false |
| 30 | Made in Heaven | - | - | - | $4,572,845 | 898 | $4,572,845 | Nov 6 | Lorimar Motion Pictures | false |
| 31 | The Dead | - | - | - | $4,370,078 | 6 | $4,370,078 | Dec 18 | Vestron Pictures | false |
| 32 | Sign 'o' the Times | - | - | - | $3,000,073 | 234 | $3,000,073 | Nov 20 | - | false |
| 33 | Stakeout | - | - | - | $2,941,195 | 1,364 | $65,673,233 | Aug 7 | Walt Disney Studios Motion Pictures | false |
| 34 | Russkies | - | - | - | $2,189,047 | 604 | $2,189,047 | Nov 6 | New Century | false |
| 35 | The Sicilian | - | - | - | $2,035,131 | 370 | $5,406,879 | Oct 23 | Twentieth Century Fox | false |
| 36 | Date with an Angel | - | - | - | $1,988,962 | 843 | $1,988,962 | Nov 20 | De Laurentiis Entertainment Group (DEG) | false |
| 37 | Weeds | - | - | - | $1,404,408 | 86 | $2,325,444 | Oct 16 | De Laurentiis Entertainment Group (DEG) | false |
| 38 | From a Whisper to a Scream | - | - | - | $1,200,737 | 137 | $1,355,728 | Sep 4 | Moviestore Entertainment | false |
| 39 | Cry Freedom | - | - | - | $1,180,156 | 479 | $5,899,797 | Nov 6 | Universal Pictures | false |
| 40 | I've Heard the Mermaids Singing | - | - | - | $1,156,937 | 27 | $1,408,491 | Sep 11 | Miramax | false |
| 41 | Housekeeping | - | - | - | $1,083,282 | 2 | $1,083,282 | Nov 25 | Columbia Pictures | false |
| 42 | Cross My Heart | - | - | - | $1,025,762 | 205 | $1,025,762 | Nov 13 | Universal Pictures | false |
| 43 | Someone to Watch Over Me | - | - | - | $1,012,349 | 894 | $10,278,549 | Oct 9 | Columbia Pictures | false |
| 44 | Moonstruck | - | - | - | $946,128 | 1,178 | $80,640,528 | Dec 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 45 | Good Morning, Vietnam | - | - | - | $792,708 | 1,598 | $123,922,370 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 46 | Steel Dawn | - | - | - | $562,187 | 290 | $562,187 | Nov 6 | Vestron Pictures | false |
| 47 | September | - | - | - | $486,434 | 15 | $486,434 | Dec 18 | Orion Pictures | false |
| 48 | Cold Steel | - | - | - | $285,885 | 135 | $285,885 | Dec 11 | Cinetel | false |
| 49 | Ironweed | - | - | - | $226,053 | 600 | $7,393,346 | Dec 18 | TriStar Pictures | false |
| 50 | Siesta | - | - | - | $32,041 | 30 | $700,000 | Nov 11 | Lorimar Motion Pictures | false |
