| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Home Alone | - | - | - | $143,592,523 | 2,173 | $285,761,243 | Nov 16 | Twentieth Century Fox | false |
| 2 | Dances with Wolves | - | - | - | $57,752,323 | 1,636 | $184,208,848 | Nov 9 | Orion Pictures | false |
| 3 | Ghost | - | - | - | $52,509,210 | 1,766 | $217,631,306 | Jul 13 | Paramount Pictures | false |
| 4 | Three Men and a Little Lady | - | - | - | $51,588,619 | 1,614 | $71,609,321 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 5 | Marked for Death | - | - | - | $46,044,396 | 1,974 | $46,044,396 | Oct 5 | Twentieth Century Fox | false |
| 6 | Rocky V | - | - | - | $40,946,358 | 2,106 | $40,946,358 | Nov 16 | United Artists | false |
| 7 | Misery | - | - | - | $37,949,926 | 1,370 | $61,276,872 | Nov 30 | Columbia Pictures | false |
| 8 | Predator 2 | - | - | - | $30,669,413 | 1,978 | $30,669,413 | Nov 21 | Twentieth Century Fox | false |
| 9 | Kindergarten Cop | - | - | - | $29,494,805 | 1,937 | $91,457,688 | Dec 22 | Universal Pictures | false |
| 10 | Child's Play 2 | - | - | - | $28,501,605 | 2,017 | $28,501,605 | Nov 9 | Universal Pictures | false |
| 11 | Memphis Belle | - | - | - | $27,441,977 | 1,368 | $27,441,977 | Oct 12 | Warner Bros. | false |
| 12 | The Godfather Part III | - | - | - | $26,837,639 | 1,922 | $66,666,062 | Dec 25 | Paramount Pictures | false |
| 13 | Jacob's Ladder | - | - | - | $26,118,851 | 1,264 | $26,118,851 | Nov 2 | TriStar Pictures | false |
| 14 | Pacific Heights | - | - | - | $25,539,132 | 1,291 | $29,381,956 | Sep 28 | Twentieth Century Fox | false |
| 15 | Fantasia 1990 Re-release | - | - | - | $25,363,371 | 481 | $25,363,371 | Oct 5 | Walt Disney Studios Motion Pictures | false |
| 16 | Goodfellas | - | - | - | $25,069,662 | 1,328 | $46,836,214 | Sep 19 | Warner Bros. | false |
| 17 | Look Who's Talking Too | - | - | - | $25,047,061 | 1,647 | $47,789,074 | Dec 14 | TriStar Pictures | false |
| 18 | Edward Scissorhands | - | - | - | $24,101,421 | 1,372 | $56,362,352 | Dec 7 | Twentieth Century Fox | false |
| 19 | Quigley Down Under | - | - | - | $21,413,105 | 1,094 | $21,413,105 | Oct 19 | Metro-Goldwyn-Mayer (MGM) | false |
| 20 | The Rescuers Down Under | - | - | - | $20,440,146 | 1,487 | $27,931,461 | Nov 16 | Walt Disney Studios Motion Pictures | false |
| 21 | Sibling Rivalry | - | - | - | $17,854,933 | 1,455 | $17,854,933 | Oct 26 | Columbia Pictures | false |
| 22 | Postcards from the Edge | - | - | - | $17,617,988 | 1,323 | $39,071,603 | Sep 14 | Columbia Pictures | false |
| 23 | White Palace | - | - | - | $17,487,531 | 892 | $17,487,531 | Oct 19 | Universal Pictures | false |
| 24 | The Rookie | - | - | - | $17,133,649 | 1,862 | $21,633,874 | Dec 7 | Warner Bros. | false |
| 25 | Avalon | - | - | - | $15,740,796 | 635 | $15,740,796 | Oct 5 | TriStar Pictures | false |
| 26 | Reversal of Fortune | - | - | - | $15,445,131 | 661 | $15,445,131 | Oct 19 | Warner Bros. | false |
| 27 | Mr. Destiny | - | - | - | $15,379,253 | 1,025 | $15,379,253 | Oct 12 | Walt Disney Studios Motion Pictures | false |
| 28 | Mermaids | - | - | - | $14,373,240 | 1,154 | $35,419,397 | Dec 14 | Orion Pictures | false |
| 29 | Graveyard Shift | - | - | - | $11,582,891 | 1,603 | $11,582,891 | Oct 26 | Paramount Pictures | false |
| 30 | Henry & June | - | - | - | $11,567,449 | 295 | $11,567,449 | Oct 5 | Universal Pictures | false |
| 31 | The Russia House | - | - | - | $9,677,043 | 768 | $22,997,992 | Dec 22 | Metro-Goldwyn-Mayer (MGM) | false |
| 32 | The Bonfire of the Vanities | - | - | - | $9,010,230 | 1,395 | $15,691,192 | Dec 22 | Warner Bros. | false |
| 33 | Flatliners | - | - | - | $8,551,745 | 1,483 | $61,489,265 | Aug 10 | Columbia Pictures | false |
| 34 | Havana | - | - | - | $6,511,157 | 835 | $9,243,140 | Dec 14 | Universal Pictures | false |
| 35 | Presumed Innocent | - | - | - | $6,319,337 | 1,451 | $86,303,188 | Jul 27 | Warner Bros. | false |
| 36 | Death Warrant | - | - | - | $5,862,727 | 1,090 | $16,853,487 | Sep 14 | Metro-Goldwyn-Mayer (MGM) | false |
| 37 | Night of the Living Dead | - | - | - | $5,835,247 | 1,544 | $5,835,247 | Oct 19 | Columbia Pictures | false |
| 38 | Narrow Margin | - | - | - | $5,142,635 | 1,253 | $10,873,237 | Sep 21 | TriStar Pictures | false |
| 39 | Miller's Crossing | - | - | - | $5,006,463 | 289 | $5,080,409 | Sep 21 | Twentieth Century Fox | false |
| 40 | Graffiti Bridge | - | - | - | $4,562,778 | 688 | $4,562,778 | Nov 2 | Warner Bros. | false |
| 41 | Pretty Woman | - | - | - | $4,444,517 | 1,811 | $178,406,268 | Mar 23 | Walt Disney Studios Motion Pictures | false |
| 42 | Almost an Angel | - | - | - | $4,095,644 | 1,373 | $6,939,946 | Dec 22 | Paramount Pictures | false |
| 43 | Welcome Home, Roxy Carmichael | - | - | - | $3,989,297 | 635 | $3,989,297 | Oct 12 | Paramount Pictures | false |
| 44 | Funny About Love | - | - | - | $3,609,256 | 1,213 | $8,141,292 | Sep 21 | Paramount Pictures | false |
| 45 | Dark Angel | - | - | - | $3,239,119 | 1,041 | $4,348,368 | Sep 28 | Triumph Releasing Corporation | false |
| 46 | Desperate Hours | - | - | - | $2,742,912 | 1,033 | $2,742,912 | Oct 5 | Metro-Goldwyn-Mayer (MGM) | false |
| 47 | King of New York | - | - | - | $2,307,726 | 119 | $2,554,476 | Sep 28 | New Line Cinema | false |
| 48 | Def by Temptation | - | - | - | $2,135,997 | 57 | $2,218,579 | May 11 | Troma | false |
| 49 | The Krays | - | - | - | $2,060,847 | 392 | $2,060,847 | Nov 9 | Miramax | false |
| 50 | Texasville | - | - | - | $1,795,817 | 354 | $2,268,181 | Sep 28 | Columbia Pictures | false |
| 51 | Tune in Tomorrow... | - | - | - | $1,794,001 | 207 | $1,794,001 | Oct 26 | Cinecom Pictures | false |
| 52 | The Nutcracker Prince | - | - | - | $1,781,694 | 906 | $1,781,694 | Nov 21 | Warner Bros. | false |
| 53 | The Hot Spot | - | - | - | $1,293,976 | 365 | $1,293,976 | Oct 12 | Orion Pictures | false |
| 54 | Bloodfist II | - | - | - | $1,292,323 | 92 | $1,292,323 | Oct 12 | Concorde Pictures | false |
| 55 | Robot Jox | - | - | - | $1,272,977 | 333 | $1,272,977 | Nov 21 | Triumph Releasing Corporation | false |
| 56 | The Icicle Thief | - | - | - | $1,197,430 | 22 | $1,231,622 | Aug 24 | Aries Films | false |
| 57 | To Sleep with Anger | - | - | - | $1,161,135 | 23 | $1,161,135 | Oct 12 | The Samuel Goldwyn Company | false |
| 58 | Corporate Affairs | - | - | - | $1,006,575 | 57 | $1,006,575 | Oct 5 | Concorde Pictures | false |
| 59 | State of Grace | - | - | - | $989,212 | 335 | $1,911,542 | Sep 14 | Orion Pictures | false |
| 60 | Awakenings | - | - | - | $969,705 | 1,330 | $52,096,475 | Dec 22 | Columbia Pictures | false |
| 61 | Waiting for the Light | - | - | - | $808,690 | 149 | $808,690 | Nov 2 | Triumph Releasing Corporation | false |
| 62 | C'est la vie | - | - | - | $805,472 | 28 | $805,472 | Nov 2 | The Samuel Goldwyn Company | false |
| 63 | The Return of Superfly | - | - | - | $610,402 | 260 | $610,402 | Nov 9 | Triton Pictures | false |
| 64 | The Tall Guy | - | - | - | $385,787 | 41 | $510,712 | Sep 21 | Miramax | false |
| 65 | The Sheltering Sky | - | - | - | $358,073 | 95 | $2,075,084 | Dec 14 | Warner Bros. | false |
| 66 | Hamlet | - | - | - | $350,798 | 624 | $20,710,451 | Dec 22 | Warner Bros. | false |
| 67 | Frankenstein Unbound | - | - | - | $334,748 | 34 | $334,748 | Nov 2 | Twentieth Century Fox | false |
| 68 | Alice | - | - | - | $224,818 | 325 | $7,331,647 | Dec 25 | Orion Pictures | false |
| 69 | Green Card | - | - | - | $186,442 | 757 | $29,888,235 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 70 | Come See the Paradise | - | - | - | $166,777 | 97 | $947,306 | Dec 25 | Twentieth Century Fox | false |
| 71 | The Grifters | - | - | - | $103,832 | 780 | $13,446,769 | Dec 7 | Miramax | false |
| 72 | Mr. & Mrs. Bridge | - | - | - | $98,086 | 240 | $7,698,010 | Nov 23 | Miramax | false |
| 73 | Hidden Agenda | - | - | - | $86,726 | 114 | $1,030,938 | Nov 21 | Hemdale | false |
| 74 | Fools of Fortune | - | - | - | $65,572 | 9 | $83,490 | Sep 14 | New Line Cinema | false |
| 75 | The Field | - | - | - | $64,336 | 40 | $1,494,399 | Dec 22 | Avenue Pictures Productions | false |
| 76 | The Long Walk Home | - | - | - | $58,182 | 272 | $4,873,620 | Dec 22 | Miramax | false |
| 77 | The Spirit of '76 | - | - | - | $52,310 | 12 | $52,310 | Oct 12 | Columbia Pictures | false |
| 78 | Vincent & Theo | - | - | - | $36,247 | 59 | $2,231,274 | Nov 2 | Hemdale | false |
| 79 | The Nasty Girl | - | - | - | $30,574 | 40 | $2,281,569 | Oct 26 | Miramax | false |
| 80 | Eating | - | - | - | $18,820 | 19 | $2,100,538 | Nov 16 | Rainbow Releasing | false |
| 81 | Just Ask for Diamond | - | - | - | $12,751 | 30 | $12,751 | Nov 30 | Castle Hill Productions | false |
