| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Final Destination | - | - | - | $733,807 | 42 | $768,364 | Oct 1 | Warner Bros. | false |
| 2 | Inglourious Basterds | - | - | - | $580,439 | 35 | $900,805 | Oct 8 | United International Pictures | false |
| 3 | Cloudy with a Chance of Meatballs | - | - | - | $577,868 | 50 | $1,044,266 | Sep 16 | Sony Pictures Releasing | false |
| 4 | District 9 | - | - | - | $516,691 | 34 | $560,397 | Oct 1 | Sony Pictures Releasing | false |
| 5 | Super | - | - | - | $304,317 | 21 | $315,828 | Oct 1 | - | false |
| 6 | The Dolphin: Story of a Dreamer | - | - | - | $303,105 | 37 | $417,949 | Oct 8 | 20th Century Fox International | false |
| 7 | This Is It | - | - | - | $238,978 | 60 | $699,407 | Oct 28 | Sony Pictures Releasing | false |
| 8 | Orphan | - | - | - | $179,029 | 25 | $722,045 | Aug 27 | Warner Bros. | false |
| 9 | Dawson Isla 10 | - | - | - | $157,339 | 21 | $433,603 | Sep 10 | - | false |
| 10 | Jennifer's Body | - | - | - | $130,268 | 34 | $143,185 | Oct 15 | 20th Century Fox International | false |
| 11 | The Hangover | - | - | - | $115,998 | 29 | $586,310 | Aug 20 | Warner Bros. | false |
| 12 | G-Force | - | - | - | $105,263 | 48 | $1,595,232 | Jul 23 | Walt Disney Pictures | false |
| 13 | The Taking of Pelham 123 | - | - | - | $104,443 | 33 | $401,304 | Sep 10 | Sony Pictures Releasing | false |
| 14 | The Ugly Truth | - | - | - | $92,737 | 25 | $370,726 | Sep 3 | Sony Pictures Releasing | false |
| 15 | Drag Me to Hell | - | - | - | $79,629 | 36 | $365,628 | Oct 29 | United International Pictures | false |
| 16 | Coco Before Chanel | - | - | - | $65,872 | 7 | $149,636 | Oct 22 | Warner Bros. | false |
| 17 | The Uninvited | - | - | - | $63,818 | 17 | $150,478 | Oct 22 | United International Pictures | false |
| 18 | My Sister's Keeper | - | - | - | $59,909 | 9 | $96,815 | Sep 24 | Warner Bros. | false |
| 19 | Solstice | - | - | - | $59,321 | 16 | $94,487 | Oct 22 | - | false |
| 20 | Ice Age: Dawn of the Dinosaurs | - | - | - | $47,051 | 89 | $7,125,445 | Jul 2 | 20th Century Fox International | false |
| 21 | Aliens in the Attic | - | - | - | $43,307 | 32 | $302,418 | Aug 27 | 20th Century Fox International | false |
| 22 | All Inclusive | - | - | - | $41,407 | 47 | $44,895 | Oct 22 | Andes Films | false |
| 23 | Tinker Bell and the Lost Treasure | - | - | - | $35,077 | 33 | $245,475 | Sep 3 | Walt Disney Pictures | false |
| 24 | The Brothers Bloom | - | - | - | $33,110 | 12 | $35,246 | Oct 8 | - | false |
| 25 | Last Chance Harvey | - | - | - | $32,849 | 12 | $158,660 | Aug 27 | - | false |
| 26 | The Maid | - | - | - | $26,639 | 20 | $429,657 | Aug 13 | Andes Films | false |
| 27 | Turistas 2009 Re-release | - | - | - | $26,220 | 7 | $29,435 | Oct 15 | - | false |
| 28 | The Time Traveler's Wife | - | - | - | $16,611 | 7 | $56,630 | Sep 10 | Warner Bros. | false |
| 29 | Fireflies in the Garden 2008 Re-release | - | - | - | $15,440 | 3 | $15,440 | Oct 15 | - | false |
| 30 | Inspector Bellamy | - | - | - | $9,129 | 2 | $9,129 | Oct 1 | - | false |
| 31 | Bandslam | - | - | - | $7,105 | 13 | $8,955 | Oct 15 | - | false |
| 32 | The Class | - | - | - | $5,103 | 2 | $15,673 | Sep 17 | - | false |
| 33 | Lorna's Silence | - | - | - | $3,751 | 3 | $18,181 | Sep 17 | - | false |
| 34 | New in Town | - | - | - | $3,598 | 8 | $32,045 | Sep 10 | - | false |
| 35 | Chef's Special 2009 Re-release | - | - | - | $2,259 | 10 | $2,259 | Oct 15 | Transeuropa | false |
| 36 | The Age of Stupid | - | - | - | $2,243 | 3 | $2,243 | Oct 22 | - | false |
| 37 | The Proposal | - | - | - | $2,229 | 29 | $293,813 | Aug 6 | Walt Disney Pictures | false |
| 38 | Boogeyman 2 | - | - | - | $2,137 | 15 | $67,452 | Sep 3 | - | false |
| 39 | Che: Part Two | - | - | - | $952 | 7 | $24,244 | Sep 3 | - | false |
| 40 | Shorts | - | - | - | $948 | 32 | $230,695 | Aug 6 | Warner Bros. | false |
| 41 | Transporter 3 | - | - | - | $601 | 10 | $39,041 | Aug 27 | - | false |
| 42 | My Bloody Valentine | - | - | - | $382 | 27 | $103,629 | Aug 20 | - | false |
