| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Alien Nation | - | - | - | $19,887,794 | 1,436 | $25,216,243 | Oct 7 | Twentieth Century Fox | false |
| 2 | Gorillas in the Mist | - | - | - | $16,313,626 | 1,085 | $24,720,479 | Sep 23 | Universal Pictures | false |
| 3 | Punchline | - | - | - | $15,194,740 | 917 | $21,042,667 | Sep 30 | Columbia Pictures | false |
| 4 | The Accused | - | - | - | $13,542,905 | 930 | $32,078,318 | Oct 14 | Paramount Pictures | false |
| 5 | Cocktail | - | - | - | $12,026,876 | 1,462 | $78,222,753 | Jul 29 | Walt Disney Studios Motion Pictures | false |
| 6 | Halloween 4: The Return of Michael Myers | - | - | - | $11,783,223 | 1,692 | $17,768,757 | Oct 21 | - | false |
| 7 | Big | - | - | - | $11,694,219 | 1,419 | $114,968,774 | Jun 3 | Twentieth Century Fox | false |
| 8 | Young Guns | - | - | - | $8,013,306 | 1,416 | $45,661,556 | Aug 12 | Twentieth Century Fox | false |
| 9 | A Fish Called Wanda | - | - | - | $7,810,723 | 1,223 | $62,493,712 | Jul 15 | Metro-Goldwyn-Mayer (MGM) | false |
| 10 | Crossing Delancey | - | - | - | $7,467,542 | 303 | $16,262,415 | Aug 26 | Warner Bros. | false |
| 11 | Die Hard | - | - | - | $6,954,194 | 1,713 | $83,008,852 | Jul 15 | Twentieth Century Fox | false |
| 12 | Who Framed Roger Rabbit | - | - | - | $5,840,223 | 1,598 | $156,452,370 | Jun 24 | Walt Disney Studios Motion Pictures | false |
| 13 | Elvira: Mistress of the Dark | - | - | - | $5,300,873 | 627 | $5,596,267 | Sep 30 | New World Pictures | false |
| 14 | A Nightmare on Elm Street 4: The Dream Master | - | - | - | $5,169,533 | 1,767 | $49,369,899 | Aug 19 | New Line Cinema | false |
| 15 | Heartbreak Hotel | - | - | - | $5,139,297 | 1,414 | $5,509,417 | Sep 30 | Walt Disney Studios Motion Pictures | false |
| 16 | Dead Ringers | - | - | - | $4,256,679 | 1,048 | $8,038,508 | Sep 23 | Twentieth Century Fox | false |
| 17 | Imagine: John Lennon | - | - | - | $3,753,977 | 561 | $3,753,977 | Oct 7 | Warner Bros. | false |
| 18 | Memories of Me | - | - | - | $3,583,303 | 723 | $3,965,604 | Sep 30 | Metro-Goldwyn-Mayer (MGM) | false |
| 19 | Things Change | - | - | - | $3,527,886 | 99 | $3,527,886 | Oct 21 | Columbia Pictures | false |
| 20 | Betrayed | - | - | - | $3,457,214 | 1,101 | $25,816,139 | Aug 26 | United Artists | false |
| 21 | Clara's Heart | - | - | - | $3,012,384 | 315 | $5,194,491 | Oct 7 | Warner Bros. | false |
| 22 | Mystic Pizza | - | - | - | $2,588,876 | 440 | $12,793,213 | Oct 21 | The Samuel Goldwyn Company | false |
| 23 | A World Apart | - | - | - | $2,291,025 | 42 | $2,326,860 | Jun 17 | Atlantic Releasing Corporation | false |
| 24 | Without a Clue | - | - | - | $2,277,474 | 491 | $8,539,181 | Oct 21 | Orion Pictures | false |
| 25 | Bat*21 | - | - | - | $2,089,648 | 516 | $3,966,256 | Oct 21 | TriStar Pictures | false |
| 26 | Running on Empty | - | - | - | $1,878,228 | 238 | $2,835,116 | Sep 9 | Warner Bros. | false |
| 27 | Pumpkinhead | - | - | - | $1,796,556 | 353 | $3,385,516 | Oct 14 | United Artists | false |
| 28 | The Last Temptation of Christ | - | - | - | $1,461,202 | 123 | $8,373,585 | Aug 12 | Universal Pictures | false |
| 29 | Feds | - | - | - | $1,048,572 | 850 | $3,838,793 | Oct 28 | Warner Bros. | false |
| 30 | Kansas | - | - | - | $606,066 | 847 | $2,432,536 | Sep 23 | Trans World Entertainment (TWE) | false |
| 31 | Track 29 | - | - | - | $376,700 | 13 | $429,028 | Sep 9 | Island Pictures | false |
| 32 | Tapeheads | - | - | - | $343,786 | 138 | $343,786 | Oct 21 | Avenue Pictures Productions | false |
| 33 | Madame Sousatzka | - | - | - | $251,083 | 123 | $3,548,238 | Oct 14 | Universal Pictures | false |
| 34 | Another Woman | - | - | - | $115,962 | 24 | $1,562,749 | Oct 14 | Orion Pictures | false |
| 35 | Salaam Bombay! | - | - | - | $44,672 | 27 | $2,080,046 | Oct 7 | Cinecom Pictures | false |
| 36 | Bird | - | - | - | $36,684 | 93 | $2,181,286 | Sep 30 | Warner Bros. | false |
| 37 | The Lair of the White Worm | - | - | - | $33,762 | 32 | $1,189,315 | Oct 21 | Vestron Pictures | false |
