| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Home Alone | - | - | - | $54,871,976 | 2,173 | $285,761,243 | Nov 16 | Twentieth Century Fox | false |
| 2 | Rocky V | - | - | - | $29,387,634 | 2,106 | $40,946,358 | Nov 16 | United Artists | false |
| 3 | Child's Play 2 | - | - | - | $23,379,741 | 2,017 | $28,501,605 | Nov 9 | Universal Pictures | false |
| 4 | Three Men and a Little Lady | - | - | - | $23,103,351 | 1,614 | $71,609,321 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 5 | Jacob's Ladder | - | - | - | $23,047,937 | 1,264 | $26,118,851 | Nov 2 | TriStar Pictures | false |
| 6 | Ghost | - | - | - | $19,604,567 | 1,766 | $217,631,306 | Jul 13 | Paramount Pictures | false |
| 7 | Dances with Wolves | - | - | - | $18,707,779 | 1,636 | $184,208,848 | Nov 9 | Orion Pictures | false |
| 8 | Predator 2 | - | - | - | $16,342,621 | 1,978 | $30,669,413 | Nov 21 | Twentieth Century Fox | false |
| 9 | Sibling Rivalry | - | - | - | $13,418,136 | 1,455 | $17,854,933 | Oct 26 | Columbia Pictures | false |
| 10 | White Palace | - | - | - | $12,071,925 | 892 | $17,487,531 | Oct 19 | Universal Pictures | false |
| 11 | Marked for Death | - | - | - | $11,745,406 | 1,974 | $46,044,396 | Oct 5 | Twentieth Century Fox | false |
| 12 | Memphis Belle | - | - | - | $11,515,419 | 1,368 | $27,441,977 | Oct 12 | Warner Bros. | false |
| 13 | The Rescuers Down Under | - | - | - | $10,116,513 | 1,487 | $27,931,461 | Nov 16 | Walt Disney Studios Motion Pictures | false |
| 14 | Quigley Down Under | - | - | - | $9,499,940 | 1,094 | $21,413,105 | Oct 19 | Metro-Goldwyn-Mayer (MGM) | false |
| 15 | Avalon | - | - | - | $9,039,684 | 635 | $15,740,796 | Oct 5 | TriStar Pictures | false |
| 16 | Reversal of Fortune | - | - | - | $8,239,479 | 661 | $15,445,131 | Oct 19 | Warner Bros. | false |
| 17 | Fantasia 1990 Re-release | - | - | - | $7,329,032 | 481 | $25,363,371 | Oct 5 | Walt Disney Studios Motion Pictures | false |
| 18 | Graveyard Shift | - | - | - | $6,020,736 | 1,603 | $11,582,891 | Oct 26 | Paramount Pictures | false |
| 19 | Mr. Destiny | - | - | - | $6,013,412 | 1,025 | $15,379,253 | Oct 12 | Walt Disney Studios Motion Pictures | false |
| 20 | Henry & June | - | - | - | $5,180,258 | 295 | $11,567,449 | Oct 5 | Universal Pictures | false |
| 21 | Graffiti Bridge | - | - | - | $4,562,778 | 688 | $4,562,778 | Nov 2 | Warner Bros. | false |
| 22 | Pacific Heights | - | - | - | $4,350,317 | 1,291 | $29,381,956 | Sep 28 | Twentieth Century Fox | false |
| 23 | Goodfellas | - | - | - | $3,818,290 | 1,328 | $46,836,214 | Sep 19 | Warner Bros. | false |
| 24 | The Krays | - | - | - | $2,060,847 | 392 | $2,060,847 | Nov 9 | Miramax | false |
| 25 | King of New York | - | - | - | $1,978,734 | 119 | $2,554,476 | Sep 28 | New Line Cinema | false |
| 26 | Misery | - | - | - | $1,857,629 | 1,370 | $61,276,872 | Nov 30 | Columbia Pictures | false |
| 27 | Tune in Tomorrow... | - | - | - | $1,719,742 | 207 | $1,794,001 | Oct 26 | Cinecom Pictures | false |
| 28 | Miller's Crossing | - | - | - | $1,409,676 | 289 | $5,080,409 | Sep 21 | Twentieth Century Fox | false |
| 29 | Robot Jox | - | - | - | $1,272,977 | 333 | $1,272,977 | Nov 21 | Triumph Releasing Corporation | false |
| 30 | The Nutcracker Prince | - | - | - | $1,182,603 | 906 | $1,781,694 | Nov 21 | Warner Bros. | false |
| 31 | The Hot Spot | - | - | - | $1,135,299 | 365 | $1,293,976 | Oct 12 | Orion Pictures | false |
| 32 | To Sleep with Anger | - | - | - | $1,134,786 | 23 | $1,161,135 | Oct 12 | The Samuel Goldwyn Company | false |
| 33 | Night of the Living Dead | - | - | - | $1,013,105 | 1,544 | $5,835,247 | Oct 19 | Columbia Pictures | false |
| 34 | Waiting for the Light | - | - | - | $808,690 | 149 | $808,690 | Nov 2 | Triumph Releasing Corporation | false |
| 35 | C'est la vie | - | - | - | $805,472 | 28 | $805,472 | Nov 2 | The Samuel Goldwyn Company | false |
| 36 | The Return of Superfly | - | - | - | $610,402 | 260 | $610,402 | Nov 9 | Triton Pictures | false |
| 37 | Frankenstein Unbound | - | - | - | $334,748 | 34 | $334,748 | Nov 2 | Twentieth Century Fox | false |
| 38 | Mr. & Mrs. Bridge | - | - | - | $98,086 | 240 | $7,698,010 | Nov 23 | Miramax | false |
| 39 | Hidden Agenda | - | - | - | $86,726 | 114 | $1,030,938 | Nov 21 | Hemdale | false |
| 40 | Vincent & Theo | - | - | - | $36,247 | 59 | $2,231,274 | Nov 2 | Hemdale | false |
| 41 | Eating | - | - | - | $18,820 | 19 | $2,100,538 | Nov 16 | Rainbow Releasing | false |
| 42 | The Nasty Girl | - | - | - | $4,367 | 40 | $2,281,569 | Oct 26 | Miramax | false |
| 43 | Just Ask for Diamond | - | - | - | $1,821 | 30 | $12,751 | Nov 30 | Castle Hill Productions | false |
