| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | What About Bob? | - | - | - | $26,976,695 | 1,805 | $63,707,829 | May 17 | Walt Disney Studios Motion Pictures | false |
| 2 | Backdraft | - | - | - | $20,982,192 | 1,983 | $77,868,585 | May 24 | Universal Pictures | false |
| 3 | Oscar | - | - | - | $16,986,285 | 1,391 | $23,562,716 | Apr 26 | Walt Disney Studios Motion Pictures | false |
| 4 | F/X2 | - | - | - | $15,901,494 | 1,502 | $21,082,165 | May 10 | Orion Pictures | false |
| 5 | Switch | - | - | - | $12,368,436 | 1,013 | $15,545,943 | May 10 | Warner Bros. | false |
| 6 | Out for Justice | - | - | - | $12,343,402 | 2,010 | $39,673,161 | Apr 12 | Warner Bros. | false |
| 7 | The Silence of the Lambs | - | - | - | $11,743,909 | 1,642 | $130,742,922 | Feb 14 | Orion Pictures | false |
| 8 | A Kiss Before Dying | - | - | - | $11,323,830 | 1,546 | $15,429,177 | Apr 26 | Universal Pictures | false |
| 9 | One Good Cop | - | - | - | $11,276,846 | 1,454 | $11,276,846 | May 3 | Walt Disney Studios Motion Pictures | false |
| 10 | Toy Soldiers | - | - | - | $11,247,656 | 1,358 | $15,073,942 | Apr 26 | TriStar Pictures | false |
| 11 | A Rage in Harlem | - | - | - | $10,438,504 | 545 | $10,438,504 | May 3 | Miramax | false |
| 12 | Madonna: Truth or Dare | - | - | - | $9,372,450 | 652 | $15,012,935 | May 10 | Miramax | false |
| 13 | Hudson Hawk | - | - | - | $9,094,955 | 2,072 | $17,218,080 | May 24 | TriStar Pictures | false |
| 14 | Dances with Wolves | - | - | - | $8,872,760 | 1,636 | $184,208,848 | Nov 9 | Orion Pictures | false |
| 15 | Thelma & Louise | - | - | - | $8,633,526 | 1,180 | $45,360,915 | May 24 | Metro-Goldwyn-Mayer (MGM) | false |
| 16 | Teenage Mutant Ninja Turtles II: The Secret of the Ooze | - | - | - | $8,457,212 | 2,868 | $78,656,813 | Mar 22 | New Line Cinema | false |
| 17 | Mortal Thoughts | - | - | - | $8,003,821 | 1,196 | $18,784,957 | Apr 19 | Columbia Pictures | false |
| 18 | Only the Lonely | - | - | - | $7,948,291 | 1,553 | $21,830,957 | May 24 | Twentieth Century Fox | false |
| 19 | New Jack City | - | - | - | $7,786,074 | 905 | $47,624,353 | Mar 8 | Warner Bros. | false |
| 20 | Stone Cold | - | - | - | $6,384,968 | 1,729 | $9,151,887 | May 17 | Columbia Pictures | false |
| 21 | Drop Dead Fred | - | - | - | $5,171,857 | 933 | $13,878,334 | May 24 | New Line Cinema | false |
| 22 | Mannequin: On the Move | - | - | - | $3,752,428 | 1,540 | $3,752,428 | May 17 | Twentieth Century Fox | false |
| 23 | Defending Your Life | - | - | - | $3,630,550 | 715 | $16,371,128 | Mar 22 | Warner Bros. | false |
| 24 | Wild Hearts Can't Be Broken | - | - | - | $3,401,053 | 1,662 | $7,294,835 | May 24 | Walt Disney Studios Motion Pictures | false |
| 25 | Sleeping with the Enemy | - | - | - | $3,095,639 | 1,545 | $101,599,005 | Feb 8 | Twentieth Century Fox | false |
| 26 | Goodfellas | - | - | - | $2,844,443 | 1,328 | $46,836,214 | Sep 19 | Warner Bros. | false |
| 27 | Home Alone | - | - | - | $2,620,172 | 2,173 | $285,761,243 | Nov 16 | Twentieth Century Fox | false |
| 28 | Eating | - | - | - | $2,081,718 | 19 | $2,100,538 | Nov 16 | Rainbow Releasing | false |
| 29 | Ju Dou | - | - | - | $1,967,488 | 39 | $1,986,433 | Mar 6 | Miramax | false |
| 30 | Spartacus 1991 Re-release | - | - | - | $1,725,683 | 52 | $1,830,650 | Apr 26 | Universal Pictures | false |
| 31 | Kindergarten Cop | - | - | - | $1,452,731 | 1,937 | $91,457,688 | Dec 22 | Universal Pictures | false |
| 32 | Soapdish | - | - | - | $1,382,808 | 1,275 | $36,489,888 | May 31 | Paramount Pictures | false |
| 33 | The Godfather Part III | - | - | - | $920,156 | 1,922 | $66,666,062 | Dec 25 | Paramount Pictures | false |
| 34 | Rosencrantz & Guildenstern Are Dead | - | - | - | $705,286 | 18 | $739,104 | Feb 8 | Cinecom Pictures | false |
| 35 | Rich Girl | - | - | - | $561,000 | 1,058 | $561,000 | May 3 | - | false |
| 36 | Sweet Talker | - | - | - | $382,510 | 409 | $382,510 | May 10 | New Line Cinema | false |
| 37 | True Colors | - | - | - | $330,027 | 9 | $418,807 | Mar 15 | Paramount Pictures | false |
| 38 | Journey of Hope | - | - | - | $247,629 | 18 | $261,718 | Apr 26 | Miramax | false |
| 39 | The Ballad of the Sad Cafe | - | - | - | $184,890 | 1 | $184,890 | May 3 | - | false |
| 40 | Open Doors | - | - | - | $102,178 | 6 | $123,470 | Mar 8 | Orion Classics | false |
| 41 | Straight Out of Brooklyn | - | - | - | $88,886 | 75 | $2,712,293 | May 22 | The Samuel Goldwyn Company | false |
| 42 | Auntie Danielle | - | - | - | $32,485 | 17 | $604,624 | May 17 | Miramax | false |
| 43 | An Angel at My Table | - | - | - | $28,692 | 20 | $1,054,638 | May 17 | Fine Line Features | false |
| 44 | Opening Night | - | - | - | $23,488 | 1 | $23,488 | May 17 | Castle Hill Productions | false |
| 45 | Truly Madly Deeply | - | - | - | $11,233 | 48 | $1,554,742 | May 3 | The Samuel Goldwyn Company | false |
| 46 | Thousand Pieces of Gold | - | - | - | $6,756 | 10 | $717,772 | Apr 26 | - | false |
| 47 | Everybody's Fine | - | - | - | $4,259 | 48 | $1,745,470 | May 31 | Miramax | false |
