| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Good Morning, Vietnam | - | - | - | $40,444,230 | 1,598 | $123,922,370 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 2 | Moonstruck | - | - | - | $23,149,503 | 1,178 | $80,640,528 | Dec 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 3 | Three Men and a Baby | - | - | - | $21,612,251 | 1,813 | $167,780,960 | Nov 25 | Walt Disney Studios Motion Pictures | false |
| 4 | The Serpent and the Rainbow | - | - | - | $16,189,901 | 1,431 | $19,595,031 | Feb 5 | Universal Pictures | false |
| 5 | Shoot to Kill | - | - | - | $16,098,307 | 1,519 | $29,300,090 | Feb 12 | Walt Disney Studios Motion Pictures | false |
| 6 | Action Jackson | - | - | - | $12,884,726 | 1,249 | $20,256,975 | Feb 12 | Lorimar Motion Pictures | false |
| 7 | She's Having a Baby | - | - | - | $12,075,110 | 1,133 | $16,031,707 | Feb 5 | Paramount Pictures | false |
| 8 | Wall Street | - | - | - | $10,532,361 | 989 | $43,848,069 | Dec 11 | Twentieth Century Fox | false |
| 9 | Broadcast News | - | - | - | $9,067,492 | 848 | $51,249,404 | Dec 18 | Twentieth Century Fox | false |
| 10 | The Last Emperor | - | - | - | $7,982,915 | 877 | $43,984,230 | Nov 20 | Columbia Pictures | false |
| 11 | For Keeps? | - | - | - | $6,821,692 | 959 | $17,514,553 | Jan 15 | TriStar Pictures | false |
| 12 | Throw Momma from the Train | - | - | - | $6,762,869 | 1,623 | $57,915,972 | Dec 11 | Orion Pictures | false |
| 13 | Hope and Glory | - | - | - | $6,457,854 | 328 | $10,021,120 | Oct 16 | Columbia Pictures | false |
| 14 | Fatal Attraction | - | - | - | $6,379,457 | 1,401 | $156,645,693 | Sep 18 | Paramount Pictures | false |
| 15 | Satisfaction | - | - | - | $6,121,631 | 1,018 | $8,253,123 | Feb 12 | Twentieth Century Fox | false |
| 16 | Overboard | - | - | - | $4,951,533 | 1,135 | $26,713,187 | Dec 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 17 | Ironweed | - | - | - | $4,704,342 | 600 | $7,393,346 | Dec 18 | TriStar Pictures | false |
| 18 | *batteries not included | - | - | - | $4,584,553 | 1,367 | $32,945,797 | Dec 18 | Universal Pictures | false |
| 19 | School Daze | - | - | - | $4,565,755 | 224 | $14,545,844 | Feb 12 | Columbia Pictures | false |
| 20 | Eddie Murphy: Raw | - | - | - | $3,409,932 | 1,494 | $50,504,655 | Dec 18 | Paramount Pictures | false |
| 21 | Frantic | - | - | - | $3,287,816 | 1,101 | $17,637,950 | Feb 26 | Warner Bros. | false |
| 22 | The Couch Trip | - | - | - | $2,928,922 | 1,332 | $11,005,304 | Jan 15 | Lorimar Motion Pictures | false |
| 23 | Cry Freedom | - | - | - | $2,923,670 | 479 | $5,899,797 | Nov 6 | Universal Pictures | false |
| 24 | Braddock: Missing in Action III | - | - | - | $2,536,939 | 1,040 | $6,193,901 | Jan 22 | Cannon Film Distributors | false |
| 25 | Planes, Trains & Automobiles | - | - | - | $2,395,766 | 1,684 | $49,530,280 | Nov 25 | Paramount Pictures | false |
| 26 | Return of the Living Dead II | - | - | - | $1,899,095 | 1,467 | $9,205,924 | Jan 15 | Lorimar Motion Pictures | false |
| 27 | A Night in the Life of Jimmy Reardon | - | - | - | $1,855,608 | 882 | $6,264,058 | Feb 26 | Twentieth Century Fox | false |
| 28 | The Unbearable Lightness of Being | - | - | - | $1,395,775 | 140 | $10,006,806 | Feb 5 | Orion Pictures | false |
| 29 | Five Corners | - | - | - | $805,543 | 13 | $969,205 | Jan 22 | - | false |
| 30 | Siesta | - | - | - | $686,284 | 30 | $700,000 | Nov 11 | Lorimar Motion Pictures | false |
| 31 | Hairspray | - | - | - | $462,060 | 227 | $6,671,108 | Feb 26 | New Line Cinema | false |
| 32 | Bloodsport | - | - | - | $394,584 | 124 | $11,806,119 | Feb 26 | Cannon Film Distributors | false |
| 33 | Gandahar | - | - | - | $341,465 | 7 | $370,698 | Jan 29 | Miramax | false |
| 34 | Promised Land | - | - | - | $272,094 | 67 | $316,199 | Jan 22 | Vestron Pictures | false |
| 35 | Aloha Summer | - | - | - | $158,512 | 123 | $418,379 | Feb 26 | - | false |
| 36 | The in Crowd | - | - | - | $136,567 | 37 | $136,567 | Feb 5 | Orion Pictures | false |
| 37 | The Manchurian Candidate 1988 Re-release | - | - | - | $114,203 | 49 | $2,757,256 | Feb 12 | Metro-Goldwyn-Mayer (MGM) | false |
| 38 | Taffin | - | - | - | $91,408 | 204 | $159,969 | Feb 26 | Metro-Goldwyn-Mayer (MGM) | false |
