| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Twins | - | - | - | $49,668,525 | 1,659 | $111,938,388 | Dec 9 | Universal Pictures | false |
| 2 | The Naked Gun: From the Files of Police Squad! | - | - | - | $42,682,610 | 1,969 | $78,756,177 | Dec 2 | Paramount Pictures | false |
| 3 | Scrooged | - | - | - | $33,288,503 | 1,897 | $60,328,558 | Nov 23 | Paramount Pictures | false |
| 4 | Rain Man | - | - | - | $33,222,479 | 1,590 | $172,825,435 | Dec 16 | Metro-Goldwyn-Mayer (MGM) | false |
| 5 | Tequila Sunrise | - | - | - | $25,613,223 | 1,411 | $41,292,551 | Dec 2 | Warner Bros. | false |
| 6 | Oliver & Company | - | - | - | $23,253,216 | 1,503 | $53,279,055 | Nov 18 | Walt Disney Studios Motion Pictures | false |
| 7 | Dirty Rotten Scoundrels | - | - | - | $18,026,148 | 1,515 | $42,039,085 | Dec 16 | Orion Pictures | false |
| 8 | The Land Before Time | - | - | - | $17,208,388 | 1,414 | $48,336,291 | Nov 18 | Universal Pictures | false |
| 9 | Working Girl | - | - | - | $11,956,349 | 1,149 | $63,779,477 | Dec 23 | Twentieth Century Fox | false |
| 10 | Child's Play | - | - | - | $11,067,651 | 1,490 | $33,244,684 | Nov 11 | United Artists | false |
| 11 | Ernest Saves Christmas | - | - | - | $8,902,774 | 1,640 | $28,202,109 | Nov 11 | Walt Disney Studios Motion Pictures | false |
| 12 | Who Framed Roger Rabbit | - | - | - | $8,027,080 | 1,598 | $156,452,370 | Jun 24 | Walt Disney Studios Motion Pictures | false |
| 13 | My Stepmother Is an Alien | - | - | - | $7,558,387 | 1,148 | $13,854,000 | Dec 9 | Columbia Pictures | false |
| 14 | Cocoon: The Return | - | - | - | $7,493,632 | 997 | $18,924,919 | Nov 23 | Twentieth Century Fox | false |
| 15 | Hellbound: Hellraiser II | - | - | - | $5,755,305 | 1,187 | $12,090,735 | Dec 23 | New World Pictures | false |
| 16 | The Accused | - | - | - | $5,351,074 | 930 | $32,078,318 | Oct 14 | Paramount Pictures | false |
| 17 | Mystic Pizza | - | - | - | $3,217,465 | 440 | $12,793,213 | Oct 21 | The Samuel Goldwyn Company | false |
| 18 | Iron Eagle II | - | - | - | $2,317,636 | 878 | $10,497,324 | Nov 11 | TriStar Pictures | false |
| 19 | A Cry in the Dark | - | - | - | $2,234,397 | 334 | $6,908,797 | Nov 11 | Warner Bros. | false |
| 20 | High Spirits | - | - | - | $2,209,288 | 826 | $8,578,231 | Nov 18 | TriStar Pictures | false |
| 21 | I'm Gonna Git You Sucka | - | - | - | $2,007,044 | 266 | $13,030,057 | Dec 16 | United Artists | false |
| 22 | 1969 | - | - | - | $1,946,616 | 520 | $5,979,011 | Nov 18 | Atlantic Releasing Corporation | false |
| 23 | The Lair of the White Worm | - | - | - | $1,155,553 | 32 | $1,189,315 | Oct 21 | Vestron Pictures | false |
| 24 | Everybody's All-American | - | - | - | $1,116,641 | 1,123 | $12,638,294 | Nov 4 | Warner Bros. | false |
| 25 | Mississippi Burning | - | - | - | $1,003,369 | 1,134 | $34,603,943 | Dec 9 | Orion Pictures | false |
| 26 | Fresh Horses | - | - | - | $998,764 | 1,276 | $6,640,346 | Nov 18 | Columbia Pictures | false |
| 27 | Watchers | - | - | - | $940,173 | 161 | $940,173 | Dec 2 | Universal Pictures | false |
| 28 | They Live | - | - | - | $855,815 | 1,463 | $13,447,978 | Nov 4 | Universal Pictures | false |
| 29 | Beaches | - | - | - | $453,250 | 1,122 | $57,041,866 | Dec 23 | Walt Disney Studios Motion Pictures | false |
| 30 | Dangerous Liaisons | - | - | - | $330,048 | 762 | $34,670,720 | Dec 23 | Warner Bros. | false |
| 31 | The Accidental Tourist | - | - | - | $246,934 | 954 | $32,632,093 | Dec 23 | Warner Bros. | false |
| 32 | Talk Radio | - | - | - | $211,033 | 653 | $3,468,572 | Dec 23 | Universal Pictures | false |
| 33 | U2: Rattle and Hum | - | - | - | $204,528 | 1,391 | $8,600,823 | Nov 4 | Paramount Pictures | false |
| 34 | Torch Song Trilogy | - | - | - | $132,733 | 135 | $4,865,997 | Dec 16 | New Line Cinema | false |
| 35 | Pelle the Conqueror | - | - | - | $69,479 | 42 | $2,053,931 | Dec 21 | Miramax | false |
| 36 | We Think the World of You | - | - | - | $20,998 | 1 | $20,998 | Dec 22 | Cinecom Pictures | false |
| 37 | Haunted Summer | - | - | - | $9,911 | 1 | $9,911 | Dec 16 | Cannon Film Distributors | false |
