| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Free Guy | - | - | - | $81,323,882 | 4,165 | $121,626,598 | Aug 13 | 20th Century Studios | false |
| 2 | Jungle Cruise | - | - | - | $75,182,377 | 4,310 | $116,987,516 | Jul 30 | Walt Disney Studios Motion Pictures | false |
| 3 | The Suicide Squad | - | - | - | $52,713,697 | 4,019 | $55,817,425 | Aug 6 | Warner Bros. | false |
| 4 | Candyman | - | - | - | $25,732,635 | 3,569 | $61,186,570 | Aug 27 | Universal Pictures | false |
| 5 | PAW Patrol: The Movie | - | - | - | $25,348,761 | 3,189 | $40,127,371 | Aug 20 | Paramount Pictures | false |
| 6 | Don't Breathe 2 | - | - | - | $25,225,087 | 3,005 | $32,712,950 | Aug 13 | Screen Gems | false |
| 7 | Respect | - | - | - | $20,237,650 | 3,207 | $24,278,399 | Aug 13 | Metro-Goldwyn-Mayer (MGM) | false |
| 8 | Old | - | - | - | $18,020,780 | 3,379 | $48,276,510 | Jul 23 | Universal Pictures | false |
| 9 | Black Widow | - | - | - | $16,391,800 | 4,275 | $183,651,655 | Jul 9 | Walt Disney Studios Motion Pictures | false |
| 10 | The Green Knight | - | - | - | $11,622,340 | 2,798 | $17,173,321 | Jul 30 | A24 | false |
| 11 | Stillwater | - | - | - | $10,315,785 | 2,611 | $14,465,535 | Jul 30 | Focus Features | false |
| 12 | Space Jam: A New Legacy | - | - | - | $8,649,051 | 4,002 | $70,592,228 | Jul 16 | Warner Bros. | false |
| 13 | Snake Eyes | - | - | - | $7,160,703 | 3,540 | $28,264,325 | Jul 23 | Paramount Pictures | false |
| 14 | The Protégé | - | - | - | $6,103,832 | 2,577 | $7,446,823 | Aug 20 | Lionsgate | false |
| 15 | The Night House | - | - | - | $5,484,316 | 2,240 | $7,100,581 | Aug 20 | Searchlight Pictures | false |
| 16 | Escape Room: Tournament of Champions | - | - | - | $5,218,397 | 2,815 | $25,314,753 | Jul 16 | Sony Pictures Releasing | false |
| 17 | F9: The Fast Saga | - | - | - | $5,033,800 | 4,203 | $173,005,945 | Jun 25 | Universal Pictures | false |
| 18 | The Boss Baby: Family Business | - | - | - | $3,781,605 | 3,688 | $57,300,280 | Jul 2 | Universal Pictures | false |
| 19 | Reminiscence | - | - | - | $3,478,723 | 3,265 | $3,900,193 | Aug 20 | Warner Bros. | false |
| 20 | The Forever Purge | - | - | - | $2,041,055 | 3,058 | $44,539,245 | Jul 2 | Universal Pictures | false |
| 21 | A Quiet Place Part II | - | - | - | $1,464,949 | 3,744 | $160,072,261 | May 28 | Paramount Pictures | false |
| 22 | Roadrunner: A Film About Anthony Bourdain | - | - | - | $777,265 | 954 | $5,354,970 | Jul 16 | Focus Features | false |
| 23 | Cruella | - | - | - | $737,388 | 3,922 | $86,103,234 | May 28 | Walt Disney Studios Motion Pictures | false |
| 24 | If I Can't Have Love, I Want Power | - | - | - | $626,946 | 122 | $626,946 | Aug 25 | IMAX | false |
| 25 | Nine Days | - | - | - | $596,494 | 443 | $694,849 | Jul 30 | Sony Pictures Classics | false |
| 26 | Pig | - | - | - | $575,914 | 588 | $3,186,668 | Jul 16 | Neon | false |
| 27 | Little Eggs: An African Rescue | - | - | - | $485,144 | 320 | $927,154 | Aug 27 | Pantelion Films | false |
| 28 | The Conjuring: The Devil Made Me Do It | - | - | - | $351,850 | 3,280 | $65,631,050 | Jun 4 | Warner Bros. | false |
| 29 | Hitman's Wife's Bodyguard | - | - | - | $321,664 | 3,361 | $38,014,727 | Jun 16 | Lionsgate | false |
| 30 | Escape from Mogadishu | - | - | - | $209,973 | 42 | $346,271 | Aug 6 | Well Go USA Entertainment | false |
| 31 | Joe Bell | - | - | - | $190,308 | 1,094 | $1,405,488 | Jul 23 | Roadside Attractions | false |
| 32 | Raging Fire | - | - | - | $187,321 | 59 | $385,305 | Aug 13 | Well Go USA Entertainment | false |
| 33 | Ailey | - | - | - | $165,386 | 88 | $204,513 | Jul 23 | Neon | false |
| 34 | 12 Mighty Orphans | - | - | - | $149,315 | 1,047 | $3,689,637 | Jun 11 | Sony Pictures Releasing | false |
| 35 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | - | - | - | $136,312 | 752 | $2,320,649 | Jun 25 | Searchlight Pictures | false |
| 36 | Zola | - | - | - | $125,502 | 1,468 | $4,844,399 | Jun 30 | A24 | false |
| 37 | Flag Day | - | - | - | $125,118 | 196 | $424,667 | Aug 20 | United Artists Releasing | false |
| 38 | Together | - | - | - | $124,473 | 250 | $214,390 | Aug 27 | Universal Pictures | false |
| 39 | Once I Was Engaged | - | - | - | $114,964 | 32 | $254,775 | Jul 21 | Excel Entertainment | false |
| 40 | Lupin III: The First | - | - | - | $109,356 | 648 | $245,724 | Oct 16 | GKIDS | false |
| 41 | Swan Song | - | - | - | $104,641 | 48 | $126,110 | Aug 6 | Magnolia Pictures | false |
| 42 | The Lost Leonardo | - | - | - | $87,989 | 217 | $445,740 | Aug 13 | Sony Pictures Classics | false |
| 43 | Peter Rabbit 2: The Runaway | - | - | - | $85,796 | 3,346 | $40,501,717 | Jun 11 | Sony Pictures Releasing | false |
| 44 | In the Heights | - | - | - | $71,835 | 3,509 | $29,975,167 | Jun 11 | Warner Bros. | false |
| 45 | Demonic | - | - | - | $57,831 | 85 | $71,334 | Aug 20 | IFC Films | false |
| 46 | Queen Bees | - | - | - | $49,009 | 600 | $1,926,706 | Jun 11 | Gravitas Ventures | false |
| 47 | Dream Horse | - | - | - | $48,594 | 1,284 | $2,913,328 | May 21 | Bleecker Street Media | false |
| 48 | Ema | - | - | - | $42,422 | 27 | $53,437 | Aug 13 | Music Box Films | false |
| 49 | The Swimming Pool 2021 Re-release | - | - | - | $39,341 | 10 | $211,467 | May 14 | Rialto Distribution | false |
| 50 | Witnesses | - | - | - | $39,093 | 90 | $855,765 | Jun 4 | Purdie Distribution | false |
| 51 | Raya and the Last Dragon | - | - | - | $38,421 | 2,375 | $54,723,032 | Mar 5 | Walt Disney Studios Motion Pictures | false |
| 52 | Death Rider in the House of Vampires | - | - | - | $38,010 | 223 | $44,736 | Aug 27 | Atlas Distribution Company | false |
| 53 | CatVideoFest 2021 | - | - | - | $31,556 | 40 | $93,579 | Jul 23 | Oscilloscope | false |
| 54 | Without Getting Killed or Caught | - | - | - | $28,799 | 7 | $55,333 | Jul 23 | mTuckman Media | false |
| 55 | Confetti | - | - | - | $25,855 | 24 | $33,500 | Aug 20 | Dada Films | false |
| 56 | Cryptozoo | - | - | - | $25,853 | 45 | $33,765 | Aug 20 | Magnolia Pictures | false |
| 57 | John and the Hole | - | - | - | $25,003 | 42 | $25,386 | Aug 6 | IFC Films | false |
| 58 | Spirit Untamed | - | - | - | $22,540 | 3,394 | $17,716,215 | Jun 4 | Universal Pictures | false |
| 59 | Even in Dreams | - | - | - | $14,936 | 12 | $15,671 | Aug 6 | Purdie Distribution | false |
| 60 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | - | - | - | $14,453 | 2,087 | $49,505,008 | Apr 23 | FUNimation Entertainment | false |
| 61 | Bring Your Own Brigade | - | - | - | $13,375 | 27 | $13,375 | Aug 6 | Paramount Pictures | false |
| 62 | Never Gonna Snow Again | - | - | - | $12,852 | 8 | $15,901 | Jul 30 | Kino Lorber | false |
| 63 | On Broadway | - | - | - | $12,428 | 63 | $82,733 | Aug 20 | Kino Lorber | false |
| 64 | The Meaning of Hitler | - | - | - | $11,492 | 17 | $12,804 | Aug 13 | IFC Films | false |
| 65 | The Truffle Hunters | - | - | - | $10,505 | 105 | $521,202 | Mar 5 | Sony Pictures Classics | false |
| 66 | Lorelei | - | - | - | $9,745 | 11 | $12,642 | Jul 30 | Freestyle Releasing | false |
| 67 | Sabaya | - | - | - | $9,402 | 14 | $10,450 | Jul 30 | MTV Documentary Films | false |
| 68 | White as Snow | - | - | - | $7,716 | 15 | $7,881 | Aug 13 | Cohen Media Group | false |
| 69 | Settlers | - | - | - | $6,920 | 30 | $29,183 | Jul 23 | IFC Films | false |
| 70 | The Loneliest Whale: The Search for 52 | - | - | - | $6,449 | 71 | $107,798 | Jul 9 | Bleecker Street Media | false |
| 71 | Summertime | - | - | - | $6,389 | 64 | $72,012 | Jul 9 | Good Deed Entertainment | false |
| 72 | Ma Belle, My Beauty | - | - | - | $5,950 | 25 | $27,744 | Aug 20 | Good Deed Entertainment | false |
| 73 | Mama Weed | - | - | - | $5,470 | 20 | $29,151 | Jul 16 | Music Box Films | false |
| 74 | No Ordinary Man | - | - | - | $5,359 | 9 | $15,508 | Jul 16 | Oscilloscope | false |
| 75 | Enemies of the State | - | - | - | $5,135 | 13 | $8,495 | Jul 30 | IFC Films | false |
| 76 | Mandibles | - | - | - | $5,117 | 24 | $19,913 | Jul 23 | Magnet Releasing | false |
| 77 | I Carry You with Me | - | - | - | $4,975 | 111 | $166,403 | Jun 25 | Sony Pictures Classics | false |
| 78 | Baking Up Love | - | - | - | $4,313 | - | $8,770 | Aug 28 | - | false |
| 79 | Lydia Lunch: The War Is Never Over | - | - | - | $3,887 | 4 | $12,948 | Jun 30 | Kino Lorber | false |
| 80 | Naked Singularity | - | - | - | $3,050 | - | $3,050 | Aug 6 | Screen Media Films | false |
| 81 | The Red Circle 2021 Re-release | - | - | - | $3,029 | 5 | $62,850 | Jun 25 | Rialto Pictures | false |
| 82 | Casanova, Last Love | - | - | - | $2,906 | 6 | $10,924 | Jul 14 | Cohen Media Group | false |
| 83 | Werewolves Within | - | - | - | $2,873 | 270 | $575,783 | Jun 25 | IFC Films | false |
| 84 | Can You Bring It: Bill T. Jones and D-Man in the Waters | - | - | - | $1,912 | 7 | $9,723 | Jul 16 | Kino Lorber | false |
| 85 | The Incredible 25th Year of Mitzi Bearclaw | - | - | - | $1,722 | 2 | $10,368 | Feb 12 | Indican Pictures | false |
| 86 | The Perfect Candidate | - | - | - | $1,005 | 17 | $30,134 | May 14 | Music Box Films | false |
| 87 | Victim of Love | - | - | - | $891 | 1 | $5,016 | Jul 23 | Indican Pictures | false |
| 88 | The Ladykillers 2021 Re-release | - | - | - | $777 | 3 | $23,213 | Jun 4 | Rialto Pictures | false |
| 89 | The Dry | - | - | - | $475 | 186 | $364,237 | May 21 | IFC Films | false |
| 90 | Secret Agent Dingledorf and His Trusty Dog Splat | - | - | - | $460 | 30 | $13,760 | Jul 2 | Integrity Releasing | false |
| 91 | Summer of 85 | - | - | - | $195 | 23 | $71,788 | Jun 18 | Music Box Films | false |
| 92 | The East | - | - | - | $180 | 2 | $180 | Aug 13 | Magnolia Pictures | false |
| 93 | Shiva Baby | - | - | - | $146 | 27 | $159,294 | Apr 2 | Utopia | false |
| 94 | Mission Stories | - | - | - | $52 | 44 | $87,059 | May 7 | Excel Entertainment | false |
