| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Rio | - | - | - | $524,093 | 11 | $776,450 | Apr 8 | 20th Century Fox International | false |
| 2 | Just Go with It | - | - | - | $143,478 | 7 | $244,048 | Apr 15 | Sony Pictures Releasing | false |
| 3 | Hall Pass | - | - | - | $134,604 | 5 | $185,947 | Apr 1 | Warner Bros. | false |
| 4 | Reus | - | - | - | $107,884 | 4 | $170,271 | Mar 25 | - | false |
| 5 | Justin Bieber: Never Say Never | - | - | - | $70,992 | 6 | $107,212 | Mar 25 | Paramount Pictures International | false |
| 6 | Whatever Works | - | - | - | $63,672 | 5 | $128,240 | Apr 15 | - | false |
| 7 | Unknown | - | - | - | $53,430 | 6 | $165,932 | Mar 4 | Warner Bros. | false |
| 8 | Hop | - | - | - | $48,926 | 5 | $65,284 | Apr 15 | Universal Pictures International (UPI) | false |
| 9 | The Concert | - | - | - | $46,217 | 2 | $106,725 | Apr 8 | - | false |
| 10 | The Hedgehog | - | - | - | $35,012 | 2 | $66,347 | Mar 25 | - | false |
| 11 | No Strings Attached | - | - | - | $30,706 | 5 | $171,800 | Feb 25 | Paramount Pictures International | false |
| 12 | The King's Speech | - | - | - | $30,693 | 5 | $419,050 | Jan 21 | - | false |
| 13 | I Am Number Four | - | - | - | $30,213 | 5 | $30,213 | Apr 8 | Walt Disney Pictures | false |
| 14 | Red Riding Hood | - | - | - | $27,065 | 5 | $41,734 | Apr 21 | Warner Bros. | false |
| 15 | Big Mommas: Like Father, Like Son | - | - | - | $21,585 | 4 | $55,768 | Mar 18 | 20th Century Fox International | false |
| 16 | Stone | - | - | - | $21,025 | 3 | $26,226 | Apr 21 | - | false |
| 17 | Thor | - | - | - | $21,019 | 6 | $82,485 | Apr 28 | Paramount Pictures International | false |
| 18 | Rango | - | - | - | $16,239 | 6 | $93,287 | Mar 4 | Paramount Pictures International | false |
| 19 | Somewhere | - | - | - | $13,891 | 5 | $26,183 | Mar 25 | Universal Pictures International (UPI) | false |
| 20 | The Rite | - | - | - | $13,867 | 6 | $177,282 | Feb 18 | Warner Bros. | false |
| 21 | The Silent House | - | - | - | $13,278 | 3 | $112,616 | Mar 4 | - | false |
| 22 | Battle Los Angeles | - | - | - | $11,838 | 5 | $81,753 | Mar 11 | Sony Pictures Releasing | false |
| 23 | The Last Exorcism | - | - | - | $11,510 | 3 | $11,510 | Apr 1 | - | false |
| 24 | Winnie the Pooh | - | - | - | $10,847 | 6 | $12,779 | Apr 15 | Walt Disney Pictures | false |
| 25 | I Spit on Your Grave | - | - | - | $10,109 | 2 | $10,109 | Apr 15 | - | false |
| 26 | Torrente 4: Lethal Crisis | - | - | - | $6,730 | 4 | $30,956 | Apr 28 | - | false |
| 27 | Water for Elephants | - | - | - | $6,617 | 3 | $30,376 | Apr 28 | 20th Century Fox International | false |
| 28 | Sucker Punch | - | - | - | $4,773 | 5 | $4,773 | Apr 8 | Warner Bros. | false |
| 29 | Mademoiselle Chambon | - | - | - | $4,691 | 1 | $26,880 | Jan 28 | - | false |
| 30 | Mars Needs Moms | - | - | - | $4,115 | 7 | $32,286 | Mar 11 | Walt Disney Pictures | false |
| 31 | Drive Angry | - | - | - | $3,428 | 5 | $23,673 | Mar 18 | Warner Bros. | false |
| 32 | Black Swan | - | - | - | $3,122 | 8 | $294,384 | Feb 4 | 20th Century Fox International | false |
| 33 | Biutiful | - | - | - | $3,033 | 4 | $41,876 | Mar 4 | - | false |
| 34 | 22 Bullets | - | - | - | $2,923 | 3 | $16,970 | Mar 18 | - | false |
| 35 | Devil | - | - | - | $2,636 | 5 | $17,633 | Mar 18 | Universal Pictures International (UPI) | false |
| 36 | A Turtle's Tale: Sammy's Adventures | - | - | - | $2,414 | 5 | $76,272 | Feb 18 | - | false |
| 37 | Remembering the Children | - | - | - | $2,279 | 1 | $2,279 | Apr 8 | - | false |
| 38 | Inside Job | - | - | - | $1,876 | 1 | $20,172 | Apr 29 | Sony Pictures Releasing | false |
| 39 | Yogi Bear | - | - | - | $1,795 | 9 | $227,738 | Jan 28 | Warner Bros. | false |
| 40 | Puzzle | - | - | - | $1,635 | 1 | $1,635 | Apr 1 | - | false |
| 41 | Father of My Children | - | - | - | $1,552 | 1 | $1,552 | Apr 8 | - | false |
| 42 | Tangled | - | - | - | $1,539 | 9 | $298,901 | Jan 7 | Walt Disney Pictures | false |
| 43 | Aniceto 2011 Re-release | - | - | - | $595 | 1 | $6,658 | Mar 4 | - | false |
| 44 | You Will Meet a Tall Dark Stranger | - | - | - | $403 | 4 | $150,604 | Dec 24 | - | false |
| 45 | Winter's Bone | - | - | - | $198 | 3 | $47,870 | Feb 4 | - | false |
