| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Monsters vs. Aliens | - | - | - | $182,939 | 10 | $218,719 | Apr 3 | Paramount Pictures International | false |
| 2 | Gran Torino | - | - | - | $64,542 | 7 | $133,412 | Mar 20 | Warner Bros. | false |
| 3 | Paul Blart: Mall Cop | - | - | - | $49,978 | 8 | $81,975 | Apr 9 | Sony Pictures Releasing | false |
| 4 | Slumdog Millionaire | - | - | - | $42,208 | 6 | $285,996 | Feb 13 | - | false |
| 5 | The International | - | - | - | $39,873 | 6 | $56,028 | Mar 27 | Sony Pictures Releasing | false |
| 6 | Righteous Kill | - | - | - | $34,563 | 5 | $57,520 | Apr 17 | - | false |
| 7 | Hotel for Dogs | - | - | - | $30,112 | 6 | $59,054 | Mar 20 | Paramount Pictures International | false |
| 8 | Confessions of a Shopaholic | - | - | - | $28,066 | 5 | $38,072 | Mar 27 | Walt Disney Pictures | false |
| 9 | Dragonball Evolution | - | - | - | $24,809 | 5 | $35,681 | Apr 10 | 20th Century Fox International | false |
| 10 | Underworld: Rise of the Lycans | - | - | - | $20,630 | 3 | $21,169 | Apr 3 | Sony Pictures Releasing | false |
| 11 | Stranded | - | - | - | $18,996 | 8 | $99,970 | Mar 6 | - | false |
| 12 | Flawless | - | - | - | $15,096 | 4 | $51,122 | Apr 24 | - | false |
| 13 | Elegy | - | - | - | $13,563 | 2 | $22,332 | Mar 27 | - | false |
| 14 | Deception | - | - | - | $13,485 | 3 | $21,663 | Apr 17 | - | false |
| 15 | Inkheart | - | - | - | $12,210 | 4 | $12,459 | Apr 3 | - | false |
| 16 | Watchmen | - | - | - | $11,207 | 5 | $13,224 | Apr 17 | Paramount Pictures International | false |
| 17 | Appaloosa | - | - | - | $10,157 | 4 | $10,157 | Apr 3 | - | false |
| 18 | Hunting and Gathering | - | - | - | $9,115 | 2 | $18,589 | Mar 20 | - | false |
| 19 | The Pink Panther 2 | - | - | - | $5,400 | 10 | $99,408 | Feb 13 | Sony Pictures Releasing | false |
| 20 | The Secret Life of Bees | - | - | - | $5,099 | 3 | $7,102 | Apr 9 | 20th Century Fox International | false |
| 21 | Disco | - | - | - | $4,860 | 2 | $4,860 | Apr 3 | - | false |
| 22 | My Mom's New Boyfriend | - | - | - | $4,810 | 3 | $12,318 | Apr 17 | - | false |
| 23 | Bride Wars | - | - | - | $4,751 | 6 | $59,343 | Mar 6 | 20th Century Fox International | false |
| 24 | Seven Pounds | - | - | - | $4,699 | 6 | $72,117 | Feb 27 | - | false |
| 25 | Rudo y Cursi | - | - | - | $3,990 | 5 | $4,663 | Apr 24 | Universal Pictures International (UPI) | false |
| 26 | Earth | - | - | - | $3,908 | 1 | $15,029 | Apr 24 | Walt Disney Pictures | false |
| 27 | Saw V | - | - | - | $3,764 | 5 | $21,538 | Mar 13 | Walt Disney Pictures | false |
| 28 | U2 3D | - | - | - | $2,558 | 1 | $43,539 | Feb 6 | - | false |
| 29 | Lamb of God | - | - | - | $2,535 | 3 | $5,031 | Apr 24 | - | false |
| 30 | The Duchess | - | - | - | $1,890 | 2 | $3,640 | Mar 27 | - | false |
| 31 | Coraline | - | - | - | $867 | 7 | $17,045 | Mar 13 | - | false |
| 32 | Vicky Cristina Barcelona | - | - | - | $676 | 7 | $210,453 | Jan 30 | - | false |
| 33 | Death Defying Acts | - | - | - | $645 | 4 | $7,101 | Mar 13 | - | false |
| 34 | Bedtime Stories | - | - | - | $591 | 7 | $121,022 | Jan 30 | - | false |
| 35 | Madagascar: Escape 2 Africa | - | - | - | $553 | 11 | $264,231 | Dec 5 | Paramount Pictures International | false |
| 36 | Sex Drive | - | - | - | $376 | 2 | $2,329 | Mar 27 | - | false |
| 37 | Marley & Me | - | - | - | $41 | 5 | $87,004 | Feb 6 | - | false |
