| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | Coco | $210,460,015 | 3,987 | $50,802,605 | 3,987 | Nov 22, 2017 | Walt Disney Studios Motion Pictures |
| 2 | We're the Millers | $150,394,119 | 3,445 | $26,419,396 | 3,260 | Aug 7, 2013 | Warner Bros. |
| 3 | Traffic | $124,115,725 | 1,755 | $184,725 | 4 | Dec 27, 2000 | USA Films |
| 4 | Beverly Hills Chihuahua | $94,514,402 | 3,239 | $29,300,465 | 3,215 | Oct 3, 2008 | Walt Disney Studios Motion Pictures |
| 5 | The Mask of Zorro | $94,095,523 | 2,515 | $22,525,855 | 2,515 | Jul 17, 1998 | Sony Pictures Releasing |
| 6 | Nacho Libre | $80,197,993 | 3,083 | $28,309,599 | 3,070 | Jun 16, 2006 | Paramount Pictures |
| 7 | Man on Fire | $77,911,774 | 2,986 | $22,751,490 | 2,980 | Apr 21, 2004 | Twentieth Century Fox |
| 8 | The Mexican | $66,845,033 | 3,162 | $20,108,829 | 2,951 | Mar 2, 2001 | DreamWorks Distribution |
| 9 | Once Upon a Time in Mexico | $56,359,780 | 3,289 | $23,424,118 | 3,282 | Sep 12, 2003 | Sony Pictures Releasing |
| 10 | Sicario | $46,889,293 | 2,620 | $401,288 | 6 | Sep 18, 2015 | Lionsgate |
| 11 | Three Amigos! | $39,246,734 | 1,466 | $5,939,000 | 1,385 | Dec 12, 1986 | Orion Pictures |
| 12 | Frida | $25,885,000 | 794 | $205,996 | 5 | Oct 25, 2002 | Miramax |
| 13 | From Dusk Till Dawn | $25,836,616 | 2,007 | $10,240,805 | 2,004 | Jan 19, 1996 | Miramax |
| 14 | Desperado | $25,405,445 | 2,027 | $7,910,446 | 2,027 | Aug 25, 1995 | Sony Pictures Releasing |
| 15 | Pure Luck | $22,641,969 | 1,569 | $5,010,810 | 1,561 | Aug 9, 1991 | Universal Pictures |
| 16 | Revenge | $15,645,616 | 1,382 | $6,086,672 | 1,379 | Feb 16, 1990 | Columbia Pictures |
| 17 | All the Pretty Horses | $15,540,353 | 1,593 | $1,304,971 | 1,483 | Dec 25, 2000 | Miramax |
| 18 | Lone Star | $12,408,986 | 143 | $232,184 | 21 | Jun 21, 1996 | Sony Pictures Classics |
| 19 | The Border | $6,118,683 | 888 | $516,014 | 84 | Jan 29, 1982 | Universal Pictures |
| 20 | The Way of the Gun | $6,055,661 | 1,565 | $2,150,979 | 1,515 | Sep 8, 2000 | Artisan Entertainment |
| 21 | The Real Cancun | $3,825,421 | 2,261 | $2,300,000 | 2,261 | Apr 25, 2003 | New Line Cinema |
| 22 | Old Gringo | $3,574,256 | 237 | $1,151,749 | 237 | Oct 6, 1989 | Columbia Pictures |
| 23 | El Mariachi | $2,040,920 | 88 | $312,528 | 66 | Feb 26, 1993 | Columbia Pictures |
| 24 | Bulletproof | $807,947 | 268 | $421,302 | 268 | May 13, 1988 | Universal Pictures |
| 25 | Tequila Body Shots | $9,037 | - | - | - | May 7, 1999 | - |
