| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | Hannibal | $165,092,268 | 3,292 | $58,003,121 | 3,230 | Feb 9, 2001 | Metro-Goldwyn-Mayer (MGM) |
| 2 | The Silence of the Lambs | $130,742,922 | 1,642 | $13,766,814 | 1,497 | Feb 14, 1991 | Orion Pictures |
| 3 | Basic Instinct | $117,727,224 | 1,884 | $15,129,385 | 1,567 | Mar 20, 1992 | TriStar Pictures |
| 4 | Seven | $100,125,643 | 2,528 | $13,949,807 | 2,441 | Sep 22, 1995 | New Line Cinema |
| 5 | Red Dragon | $93,149,898 | 3,363 | $36,540,945 | 3,357 | Oct 4, 2002 | Universal Pictures |
| 6 | Saw II | $87,039,965 | 2,949 | $31,725,652 | 2,949 | Oct 28, 2005 | Lionsgate |
| 7 | Saw III | $80,238,724 | 3,167 | $33,610,391 | 3,167 | Oct 27, 2006 | Lionsgate |
| 8 | The Bone Collector | $66,518,655 | 2,623 | $16,712,020 | 2,587 | Nov 5, 1999 | Universal Pictures |
| 9 | Saw IV | $63,300,095 | 3,183 | $31,756,764 | 3,183 | Oct 26, 2007 | Lionsgate |
| 10 | The Cell | $61,334,059 | 2,476 | $17,515,050 | 2,411 | Aug 18, 2000 | New Line Cinema |
| 11 | Kiss the Girls | $60,527,873 | 2,406 | $13,215,167 | 2,271 | Oct 3, 1997 | Paramount Pictures |
| 12 | Sea of Love | $58,571,513 | 1,439 | $10,017,840 | 1,246 | Sep 15, 1989 | Universal Pictures |
| 13 | Saw | $55,185,045 | 2,467 | $18,276,468 | 2,315 | Oct 29, 2004 | Lionsgate |
| 14 | Identity | $52,159,536 | 2,733 | $16,225,263 | 2,733 | Apr 25, 2003 | Sony Pictures Releasing |
| 15 | Natural Born Killers | $50,282,766 | 1,904 | $11,166,687 | 1,510 | Aug 26, 1994 | Warner Bros. |
| 16 | Saw 3D | $45,710,178 | 2,808 | $22,530,123 | 2,808 | Oct 29, 2010 | Lionsgate |
| 17 | Psycho II | $34,725,000 | 1,488 | $8,310,244 | 1,448 | Jun 3, 1983 | Universal Pictures |
| 18 | Monster | $34,469,210 | 1,093 | $86,831 | 4 | Dec 24, 2003 | Newmarket Films |
| 19 | Zodiac | $33,080,084 | 2,379 | $13,395,610 | 2,362 | Mar 2, 2007 | Paramount Pictures |
| 20 | Taking Lives | $32,682,342 | 2,705 | $11,458,465 | 2,705 | Mar 19, 2004 | Warner Bros. |
| 21 | Copycat | $32,051,917 | 1,661 | $5,170,522 | 1,390 | Oct 27, 1995 | Warner Bros. |
| 22 | Dressed to Kill | $31,899,000 | - | - | - | Jun 23, 1980 | Orion Pictures |
| 23 | From Hell | $31,602,566 | 2,334 | $11,014,818 | 2,305 | Oct 19, 2001 | Twentieth Century Fox |
| 24 | The Watcher | $28,946,615 | 2,777 | $9,062,295 | 2,742 | Sep 8, 2000 | Universal Pictures |
| 25 | Untraceable | $28,687,835 | 2,368 | $11,354,069 | 2,368 | Jan 25, 2008 | Screen Gems |
| 26 | Mr. Brooks | $28,549,298 | 2,453 | $10,017,067 | 2,453 | Jun 1, 2007 | Metro-Goldwyn-Mayer (MGM) |
| 27 | Hannibal Rising | $27,670,986 | 3,003 | $13,051,650 | 3,003 | Feb 9, 2007 | - |
| 28 | Blood Work | $26,235,081 | 2,525 | $7,312,413 | 2,525 | Aug 9, 2002 | Warner Bros. |
| 29 | Alex Cross | $25,888,412 | 2,541 | $11,396,768 | 2,539 | Oct 19, 2012 | Lionsgate |
| 30 | Twisted | $25,198,598 | 2,704 | $8,904,299 | 2,703 | Feb 27, 2004 | Paramount Pictures |
| 31 | Psycho | $21,485,655 | 2,489 | $10,031,850 | 2,477 | Dec 4, 1998 | Universal Pictures |
| 32 | The Pledge | $19,733,089 | 1,410 | $5,765,347 | 1,275 | Jan 19, 2001 | Warner Bros. |
| 33 | Summer of Sam | $19,288,130 | 1,536 | $5,952,452 | 1,536 | Jul 2, 1999 | Walt Disney Studios Motion Pictures |
| 34 | The Raven | $16,008,272 | 2,209 | $7,289,642 | 2,203 | Apr 27, 2012 | Relativity Media |
| 35 | American Psycho | $15,070,285 | 1,242 | $4,961,015 | 1,236 | Apr 14, 2000 | Lionsgate |
| 36 | The Vanishing | $14,543,394 | 1,658 | $5,009,928 | 1,656 | Feb 5, 1993 | Twentieth Century Fox |
| 37 | Psycho III | $14,481,606 | 1,408 | $3,238,400 | 1,408 | Jul 4, 1986 | Universal Pictures |
| 38 | Gone | $11,682,205 | 2,186 | $4,770,360 | 2,186 | Feb 24, 2012 | Lionsgate |
| 39 | So I Married an Axe Murderer | $11,585,483 | 1,355 | $3,466,930 | 1,349 | Jul 30, 1993 | TriStar Pictures |
| 40 | Hell Fest | $11,107,431 | 2,297 | $5,130,963 | 2,297 | Sep 28, 2018 | Lionsgate |
| 41 | Suspect Zero | $8,725,813 | 1,501 | $3,446,375 | 1,500 | Aug 27, 2004 | Paramount Pictures |
| 42 | Manhunter | $8,620,929 | 779 | $2,204,400 | 779 | Aug 15, 1986 | De Laurentiis Entertainment Group (DEG) |
| 43 | Serial Mom | $7,820,688 | 560 | $2,040,450 | 502 | Apr 13, 1994 | - |
| 44 | The Snowman | $6,700,035 | 1,815 | $3,372,565 | 1,812 | Oct 20, 2017 | Universal Pictures |
| 45 | Basic Instinct 2 | $5,971,336 | 1,453 | $3,201,420 | 1,453 | Mar 31, 2006 | Sony Pictures Releasing |
| 46 | In the Cut | $4,750,602 | 825 | $97,625 | 6 | Oct 22, 2003 | Screen Gems |
| 47 | Kalifornia | $2,395,231 | 359 | $1,159,133 | 359 | Sep 3, 1993 | Gramercy Pictures (I) |
| 48 | The Rosary Murders | $1,730,337 | - | - | - | Aug 28, 1987 | New Line Cinema |
| 49 | Nightwatch | $1,179,002 | 300 | $585,733 | 300 | Apr 17, 1998 | Miramax |
| 50 | The Villain | $730,530 | 104 | $414,116 | 104 | Jun 27, 2014 | Eros Worldwide |
| 51 | Henry: Portrait of a Serial Killer | $609,939 | 8 | - | - | Jan 5, 1990 | - |
| 52 | The Minus Man | $370,668 | 45 | $40,292 | 5 | Sep 10, 1999 | Artisan Entertainment |
| 53 | 7 Khoon Maaf | $270,207 | 68 | $164,153 | 65 | Feb 18, 2011 | UTV Motion Pictures |
| 54 | Filth to Ashes, Flesh to Dust | $202,531 | 11 | $86,086 | 11 | Sep 30, 2011 | Nocturnal Features |
| 55 | The House That Jack Built | $170,113 | 140 | - | - | Nov 28, 2018 | IFC Films |
| 56 | Malevolence | $127,287 | 10 | $13,445 | 2 | Sep 10, 2004 | - |
| 57 | Blue Caprice | $93,995 | 36 | $13,400 | 1 | Sep 13, 2013 | IFC Films |
| 58 | Office Killer | $76,054 | - | - | - | Dec 3, 1997 | Strand Releasing |
| 59 | The Zodiac | $45,148 | 10 | $20,578 | 10 | Mar 17, 2006 | THINKFilm |
| 60 | Close Your Eyes | $41,392 | 17 | $21,980 | 17 | Apr 23, 2004 | First Look International |
| 61 | 36 Saints | $11,640 | 9 | $7,373 | 9 | Sep 6, 2013 | Active Fox Productions |
| 62 | Good Neighbours | $7,072 | 3 | $2,953 | 3 | Jul 29, 2011 | Magnolia Pictures |
| 63 | The Hillside Strangler | $4,143 | 1 | $306 | 1 | Sep 24, 2004 | Tartan |
