| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | Black Panther | $700,059,566 | 4,084 | $202,003,951 | 4,020 | Feb 16, 2018 | Walt Disney Studios Motion Pictures |
| 2 | Captain Marvel | $426,829,839 | 4,310 | $153,433,423 | 4,310 | Mar 8, 2019 | Walt Disney Studios Motion Pictures |
| 3 | Wonder Woman | $412,563,408 | 4,165 | $103,251,471 | 4,165 | Jun 2, 2017 | Warner Bros. |
| 4 | Spider-Man | $403,706,375 | 3,876 | $114,844,116 | 3,615 | May 3, 2002 | Sony Pictures Releasing |
| 5 | Deadpool | $363,070,709 | 3,856 | $132,434,639 | 3,558 | Feb 12, 2016 | Twentieth Century Fox |
| 6 | Aquaman | $335,061,807 | 4,184 | $67,873,522 | 4,125 | Dec 21, 2018 | Warner Bros. |
| 7 | Guardians of the Galaxy | $333,176,600 | 4,088 | $94,320,883 | 4,080 | Aug 1, 2014 | Walt Disney Studios Motion Pictures |
| 8 | Suicide Squad | $325,100,054 | 4,255 | $133,682,248 | 4,255 | Aug 5, 2016 | Warner Bros. |
| 9 | Iron Man | $318,604,126 | 4,154 | $98,618,668 | 4,105 | May 2, 2008 | Paramount Pictures |
| 10 | Man of Steel | $291,045,518 | 4,207 | $116,619,362 | 4,207 | Jun 14, 2013 | Warner Bros. |
| 11 | The Amazing Spider-Man | $262,030,663 | 4,318 | $62,004,688 | 4,318 | Jul 3, 2012 | Sony Pictures Releasing |
| 12 | Batman | $251,188,924 | 2,201 | $40,489,746 | 2,194 | Jun 23, 1989 | Warner Bros. |
| 13 | Doctor Strange | $232,641,920 | 3,882 | $85,058,311 | 3,882 | Nov 4, 2016 | Walt Disney Studios Motion Pictures |
| 14 | Big Hero 6 | $222,527,828 | 3,773 | $56,215,889 | 3,761 | Nov 7, 2014 | Walt Disney Studios Motion Pictures |
| 15 | Venom | $213,515,506 | 4,250 | $80,255,756 | 4,250 | Oct 5, 2018 | Sony Pictures Releasing |
| 16 | Batman Begins | $205,343,774 | 3,858 | $48,745,440 | 3,858 | Jun 15, 2005 | Warner Bros. |
| 17 | Teenage Mutant Ninja Turtles | $191,204,754 | 3,980 | $65,575,105 | 3,845 | Aug 8, 2014 | Paramount Pictures |
| 18 | Thor | $181,030,624 | 3,963 | $65,723,338 | 3,955 | May 6, 2011 | Paramount Pictures |
| 19 | Ant-Man | $180,202,163 | 3,868 | $57,225,526 | 3,856 | Jul 17, 2015 | Walt Disney Studios Motion Pictures |
| 20 | X-Men Origins: Wolverine | $179,883,157 | 4,102 | $85,058,003 | 4,099 | May 1, 2009 | Twentieth Century Fox |
| 21 | Captain America: The First Avenger | $176,654,505 | 3,715 | $65,058,524 | 3,715 | Jul 22, 2011 | Paramount Pictures |
| 22 | X-Men | $157,299,718 | 3,112 | $54,471,475 | 3,025 | Jul 14, 2000 | Twentieth Century Fox |
| 23 | Fantastic Four | $154,696,080 | 3,619 | $56,061,504 | 3,602 | Jul 8, 2005 | Twentieth Century Fox |
| 24 | X-Men: First Class | $146,408,305 | 3,692 | $55,101,604 | 3,641 | Jun 3, 2011 | Twentieth Century Fox |
| 25 | Shazam! | $140,371,656 | 4,306 | $53,505,326 | 4,217 | Apr 5, 2019 | Warner Bros. |
| 26 | Teenage Mutant Ninja Turtles | $135,265,915 | 2,377 | $25,398,367 | 2,006 | Mar 30, 1990 | New Line Cinema |
| 27 | The Incredible Hulk | $134,806,913 | 3,508 | $55,414,050 | 3,505 | Jun 13, 2008 | Universal Pictures |
| 28 | Wanted | $134,508,551 | 3,185 | $50,927,085 | 3,175 | Jun 27, 2008 | Universal Pictures |
| 29 | Superman | $134,218,018 | 817 | $7,465,343 | 508 | Dec 15, 1978 | Warner Bros. |
| 30 | Hulk | $132,177,234 | 3,674 | $62,128,420 | 3,660 | Jun 20, 2003 | Universal Pictures |
| 31 | Green Lantern | $116,601,172 | 3,816 | $53,174,303 | 3,816 | Jun 17, 2011 | Warner Bros. |
| 32 | Ghost Rider | $115,802,596 | 3,620 | $45,388,836 | 3,619 | Feb 16, 2007 | Sony Pictures Releasing |
| 33 | Daredevil | $102,543,518 | 3,474 | $40,310,419 | 3,471 | Feb 14, 2003 | Twentieth Century Fox |
| 34 | The Green Hornet | $98,780,042 | 3,584 | $33,526,876 | 3,584 | Jan 14, 2011 | Sony Pictures Releasing |
| 35 | Unbreakable | $95,011,339 | 2,708 | $30,330,771 | 2,708 | Nov 22, 2000 | Walt Disney Studios Motion Pictures |
| 36 | The Mask of Zorro | $94,095,523 | 2,515 | $22,525,855 | 2,515 | Jul 17, 1998 | Sony Pictures Releasing |
| 37 | Power Rangers | $85,364,450 | 3,693 | $40,300,288 | 3,693 | Mar 24, 2017 | Lionsgate |
| 38 | Blade | $70,087,718 | 2,389 | $17,073,856 | 2,322 | Aug 21, 1998 | New Line Cinema |
| 39 | Chronicle | $64,575,175 | 2,908 | $22,004,098 | 2,907 | Feb 3, 2012 | Twentieth Century Fox |
| 40 | Spawn | $54,870,175 | 2,604 | $19,738,749 | 2,536 | Aug 1, 1997 | New Line Cinema |
| 41 | The Crow | $50,693,129 | 2,119 | $11,774,332 | 1,573 | May 13, 1994 | Miramax |
| 42 | Kick-Ass | $48,071,303 | 3,065 | $19,828,687 | 3,065 | Apr 16, 2010 | Lionsgate |
| 43 | The Rocketeer | $46,704,056 | 1,903 | $9,600,754 | 1,616 | Jun 21, 1991 | Walt Disney Studios Motion Pictures |
| 44 | Catwoman | $40,202,379 | 3,117 | $16,728,411 | 3,117 | Jul 23, 2004 | Warner Bros. |
| 45 | The Punisher | $33,810,189 | 2,649 | $14,000,000 | 2,649 | Apr 16, 2004 | Lionsgate |
| 46 | Mystery Men | $29,762,011 | 2,142 | $10,017,865 | 2,136 | Aug 6, 1999 | Universal Pictures |
| 47 | The Powerpuff Girls Movie | $11,412,414 | 2,340 | $3,583,114 | 2,340 | Jul 3, 2002 | Warner Bros. |
