| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | Wild Hogs | $168,273,550 | 3,401 | $39,699,023 | 3,287 | Mar 2, 2007 | Walt Disney Studios Motion Pictures |
| 2 | We're the Millers | $150,394,119 | 3,445 | $26,419,396 | 3,260 | Aug 7, 2013 | Warner Bros. |
| 3 | Identity Thief | $134,506,920 | 3,230 | $34,551,025 | 3,141 | Feb 8, 2013 | Universal Pictures |
| 4 | Dumb and Dumber | $127,175,374 | 2,565 | $16,363,442 | 2,447 | Dec 16, 1994 | New Line Cinema |
| 5 | Jackass Presents: Bad Grandpa | $102,003,019 | 3,345 | $32,055,177 | 3,336 | Oct 25, 2013 | Paramount Pictures |
| 6 | Due Date | $100,539,043 | 3,365 | $32,689,406 | 3,355 | Nov 5, 2010 | Warner Bros. |
| 7 | Dumb and Dumber To | $86,208,010 | 3,188 | $36,111,775 | 3,154 | Nov 14, 2014 | Universal Pictures |
| 8 | Alvin and the Chipmunks: The Road Chip | $85,886,987 | 3,705 | $14,287,159 | 3,653 | Dec 18, 2015 | Twentieth Century Fox |
| 9 | Tammy | $84,525,432 | 3,465 | $21,577,049 | 3,465 | Jul 2, 2014 | Warner Bros. |
| 10 | Are We There Yet? | $82,674,398 | 2,810 | $18,575,214 | 2,709 | Jan 21, 2005 | Revolution Studios |
| 11 | RV | $71,726,025 | 3,651 | $16,414,767 | 3,639 | Apr 28, 2006 | Sony Pictures Releasing |
| 12 | Sideways | $71,503,593 | 1,786 | $207,042 | 4 | Oct 22, 2004 | - |
| 13 | Road Trip | $68,540,777 | 2,654 | $15,484,004 | 2,530 | May 19, 2000 | DreamWorks Distribution |
| 14 | The Muppet Movie | $65,200,000 | - | - | - | Jun 22, 1979 | Associated Film Distribution (AFD) |
| 15 | About Schmidt | $65,016,287 | 1,240 | $282,367 | 6 | Dec 13, 2002 | New Line Cinema |
| 16 | Vacation | $61,399,552 | 1,253 | $8,333,358 | 1,175 | Jul 29, 1983 | Warner Bros. |
| 17 | Little Miss Sunshine | $59,891,098 | 1,602 | $370,998 | 7 | Jul 26, 2006 | - |
| 18 | Vacation | $58,884,188 | 3,430 | $14,681,108 | 3,411 | Jul 29, 2015 | Warner Bros. |
| 19 | The Blues Brothers | $57,229,890 | 594 | $4,858,152 | 594 | Jun 20, 1980 | Universal Pictures |
| 20 | Rat Race | $56,618,055 | 2,551 | $11,662,094 | 2,550 | Aug 17, 2001 | Paramount Pictures |
| 21 | Forces of Nature | $52,900,680 | 2,335 | $13,510,728 | 2,058 | Mar 19, 1999 | DreamWorks Distribution |
| 22 | Planes, Trains & Automobiles | $49,530,280 | 1,684 | $7,009,482 | 1,118 | Nov 25, 1987 | Paramount Pictures |
| 23 | College Road Trip | $45,610,425 | 2,706 | $13,601,419 | 2,706 | Mar 7, 2008 | Walt Disney Studios Motion Pictures |
| 24 | Pee-wee's Big Adventure | $40,940,662 | 894 | $4,545,847 | 829 | Aug 9, 1985 | Warner Bros. |
| 25 | Midnight Run | $38,413,606 | 1,161 | $5,506,290 | 1,158 | Jul 22, 1988 | Universal Pictures |
| 26 | The Guilt Trip | $37,134,215 | 2,431 | $5,290,629 | 2,431 | Dec 19, 2012 | Paramount Pictures |
| 27 | Tommy Boy | $32,679,899 | 2,186 | $8,027,843 | 2,165 | Mar 31, 1995 | Paramount Pictures |
| 28 | Johnson Family Vacation | $31,203,964 | 1,326 | $9,375,307 | 1,317 | Apr 7, 2004 | - |
| 29 | Jay and Silent Bob Strike Back | $30,085,147 | 2,765 | $11,018,543 | 2,765 | Aug 24, 2001 | Miramax |
| 30 | Joe Dirt | $27,087,695 | 2,638 | $8,016,008 | 2,638 | Apr 11, 2001 | Sony Pictures Releasing |
| 31 | Nurse Betty | $25,170,054 | 1,491 | $7,145,950 | 1,459 | Sep 8, 2000 | USA Films |
| 32 | Kingpin | $25,023,434 | 1,975 | $5,582,079 | 1,956 | Jul 26, 1996 | Metro-Goldwyn-Mayer (MGM) |
| 33 | My Fellow Americans | $22,313,201 | 1,915 | $2,860,334 | 1,915 | Dec 20, 1996 | Warner Bros. |
| 34 | The Odd Couple II | $18,912,328 | 1,852 | $4,810,288 | 1,650 | Apr 10, 1998 | Paramount Pictures |
| 35 | Harold & Kumar Go to White Castle | $18,250,550 | 2,163 | $5,200,000 | 2,135 | Jul 30, 2004 | New Line Cinema |
| 36 | The Sure Thing | $18,135,531 | 1,115 | $3,124,782 | 1,115 | Mar 1, 1985 | Metro-Goldwyn-Mayer (MGM) |
| 37 | EuroTrip | $17,771,387 | 2,544 | $6,711,384 | 2,512 | Feb 20, 2004 | DreamWorks Distribution |
| 38 | Nebraska | $17,654,912 | 968 | $140,401 | 4 | Nov 15, 2013 | Paramount Pictures |
| 39 | Serving Sara | $16,930,185 | 2,174 | $5,758,236 | 2,154 | Aug 23, 2002 | Paramount Pictures |
| 40 | Blues Brothers 2000 | $14,051,384 | 2,516 | $6,129,615 | 2,507 | Feb 6, 1998 | Universal Pictures |
| 41 | Broken Flowers | $13,744,960 | 433 | $780,408 | 27 | Aug 5, 2005 | Focus Features |
| 42 | Lost in America | $10,179,000 | 315 | $154,877 | 6 | Mar 15, 1985 | Warner Bros. |
| 43 | Transamerica | $9,015,303 | 656 | $46,908 | 2 | Dec 2, 2005 | The Weinstein Company |
| 44 | Play It to the Bone | $8,434,146 | 1,588 | $3,366 | 1 | Dec 25, 1999 | Walt Disney Studios Motion Pictures |
| 45 | Sex Drive | $8,402,485 | 2,421 | $3,607,164 | 2,421 | Oct 17, 2008 | Summit Entertainment |
| 46 | Something Wild | $8,362,969 | 916 | $1,825,717 | 914 | Nov 7, 1986 | Orion Pictures |
| 47 | Larger Than Life | $8,315,693 | 2,433 | $3,779,504 | 2,433 | Nov 1, 1996 | Metro-Goldwyn-Mayer (MGM) |
| 48 | Seeking a Friend for the End of the World | $7,078,738 | 1,625 | $3,822,803 | 1,625 | Jun 22, 2012 | Focus Features |
| 49 | Miss March | $4,543,320 | 1,742 | $2,409,156 | 1,742 | Mar 13, 2009 | - |
| 50 | Land Ho! | $727,594 | 73 | $34,319 | 4 | Jul 11, 2014 | Sony Pictures Classics |
| 51 | Crystal Fairy & the Magical Cactus | $202,370 | 20 | $25,052 | 2 | Jul 12, 2013 | IFC Films |
| 52 | The Puffy Chair | $194,523 | 7 | $26,029 | 7 | Jun 2, 2006 | IDP Distribution |
| 53 | Diamonds | $88,428 | 27 | $7,837 | 2 | Dec 10, 1999 | Miramax |
| 54 | The Discoverers | $50,020 | 4 | $7,166 | 1 | May 16, 2014 | Quadratic Media |
| 55 | Backseat | $12,343 | 1 | $5,816 | 1 | Mar 28, 2008 | Truly Indie |
| 56 | BuzzKill | $5,860 | 1 | $2,912 | 1 | Jan 20, 2012 | Indican Pictures |
| 57 | The Long Dumb Road | $4,667 | 1 | $4,667 | 1 | Nov 9, 2018 | The Film Arcade |
