| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | My Big Fat Greek Wedding | $241,438,208 | 2,016 | $597,362 | 108 | Apr 19, 2002 | IFC Films |
| 2 | What Women Want | $182,811,707 | 3,092 | $33,614,543 | 3,012 | Dec 15, 2000 | Paramount Pictures |
| 3 | Hitch | $179,495,555 | 3,575 | $43,142,214 | 3,575 | Feb 11, 2005 | Sony Pictures Releasing |
| 4 | Pretty Woman | $178,406,268 | 1,811 | $11,280,591 | 1,325 | Mar 23, 1990 | Walt Disney Studios Motion Pictures |
| 5 | There's Something About Mary | $176,484,651 | 2,555 | $13,740,644 | 2,186 | Jul 15, 1998 | Twentieth Century Fox |
| 6 | Crazy Rich Asians | $174,532,921 | 3,865 | $26,510,140 | 3,384 | Aug 15, 2018 | Warner Bros. |
| 7 | The Proposal | $163,958,031 | 3,158 | $33,627,598 | 3,056 | Jun 19, 2009 | Walt Disney Studios Motion Pictures |
| 8 | Sex and the City | $152,647,258 | 3,325 | $57,038,404 | 3,285 | May 30, 2008 | Warner Bros. |
| 9 | Runaway Bride | $152,257,509 | 3,240 | $35,055,556 | 3,158 | Jul 30, 1999 | Paramount Pictures |
| 10 | Knocked Up | $148,768,917 | 2,975 | $30,690,990 | 2,871 | Jun 1, 2007 | Universal Pictures |
| 11 | As Good as It Gets | $148,478,011 | 1,837 | $12,606,928 | 1,572 | Dec 23, 1997 | Sony Pictures Releasing |
| 12 | Bringing Down the House | $132,716,677 | 2,910 | $31,101,026 | 2,801 | Mar 7, 2003 | Walt Disney Studios Motion Pictures |
| 13 | Silver Linings Playbook | $132,092,958 | 2,809 | $443,003 | 16 | Nov 16, 2012 | The Weinstein Company |
| 14 | Coming to America | $128,152,301 | 2,064 | $21,404,420 | 2,064 | Jun 29, 1988 | Paramount Pictures |
| 15 | Sweet Home Alabama | $127,223,418 | 3,313 | $35,648,740 | 3,293 | Sep 27, 2002 | Walt Disney Studios Motion Pictures |
| 16 | My Best Friend's Wedding | $127,120,029 | 2,376 | $21,678,377 | 2,134 | Jun 20, 1997 | Sony Pictures Releasing |
| 17 | Sleepless in Seattle | $126,680,884 | 1,657 | $17,253,733 | 1,579 | Jun 25, 1993 | TriStar Pictures |
| 18 | Mr. Deeds | $126,293,452 | 3,239 | $37,162,787 | 3,231 | Jun 28, 2002 | Sony Pictures Releasing |
| 19 | Something's Gotta Give | $124,728,738 | 2,876 | $16,064,723 | 2,677 | Dec 12, 2003 | Sony Pictures Releasing |
| 20 | 50 First Dates | $120,908,074 | 3,612 | $39,852,237 | 3,591 | Feb 13, 2004 | Sony Pictures Releasing |
| 21 | The Break-Up | $118,703,275 | 3,146 | $39,172,785 | 3,070 | Jun 2, 2006 | Universal Pictures |
| 22 | Notting Hill | $116,089,678 | 2,786 | $21,811,180 | 2,747 | May 28, 1999 | Universal Pictures |
| 23 | You've Got Mail | $115,821,495 | 2,948 | $18,426,749 | 2,691 | Dec 18, 1998 | Warner Bros. |
| 24 | It's Complicated | $112,735,375 | 2,955 | $22,100,820 | 2,887 | Dec 25, 2009 | Universal Pictures |
| 25 | Valentine's Day | $110,485,654 | 3,665 | $56,260,707 | 3,665 | Feb 12, 2010 | Warner Bros. |
| 26 | Trainwreck | $110,212,700 | 3,171 | $30,097,040 | 3,158 | Jul 17, 2015 | Universal Pictures |
| 27 | How to Lose a Guy in 10 Days | $105,813,373 | 2,923 | $23,774,850 | 2,923 | Feb 7, 2003 | Paramount Pictures |
| 28 | Just Go with It | $103,028,109 | 3,548 | $30,514,732 | 3,548 | Feb 11, 2011 | Sony Pictures Releasing |
| 29 | Shakespeare in Love | $100,317,794 | 2,030 | $224,012 | 8 | Dec 11, 1998 | Miramax |
| 30 | Norbit | $95,673,607 | 3,145 | $34,195,434 | 3,136 | Feb 9, 2007 | DreamWorks |
| 31 | Arthur | $95,461,682 | 701 | $2,719,534 | 701 | Jul 17, 1981 | Warner Bros. |
| 32 | Sex and the City 2 | $95,347,692 | 3,445 | $31,001,870 | 3,445 | May 27, 2010 | Warner Bros. |
| 33 | Maid in Manhattan | $94,011,225 | 3,050 | $18,711,407 | 2,838 | Dec 13, 2002 | Revolution Studios |
| 34 | He's Just Not That Into You | $93,953,653 | 3,175 | $27,785,487 | 3,175 | Feb 6, 2009 | Warner Bros. |
| 35 | America's Sweethearts | $93,607,673 | 3,011 | $30,181,877 | 3,011 | Jul 20, 2001 | Revolution Studios |
| 36 | Two Weeks Notice | $93,354,851 | 2,755 | $14,328,494 | 2,755 | Dec 20, 2002 | Warner Bros. |
| 37 | When Harry Met Sally... | $92,823,546 | 1,174 | $1,094,453 | 41 | Jul 14, 1989 | Columbia Pictures |
| 38 | Think Like a Man | $91,547,205 | 2,052 | $33,636,303 | 2,015 | Apr 20, 2012 | Screen Gems |
| 39 | The Ugly Truth | $88,915,214 | 2,975 | $27,605,576 | 2,882 | Jul 24, 2009 | Sony Pictures Releasing |
| 40 | Failure to Launch | $88,715,192 | 3,202 | $24,411,322 | 3,057 | Mar 10, 2006 | Paramount Pictures |
| 41 | Along Came Polly | $88,097,164 | 3,052 | $27,721,185 | 2,984 | Jan 16, 2004 | Universal Pictures |
| 42 | Crazy, Stupid, Love. | $84,351,197 | 3,020 | $19,104,303 | 3,020 | Jul 29, 2011 | Warner Bros. |
| 43 | While You Were Sleeping | $81,057,016 | 2,086 | $9,288,915 | 1,421 | Apr 21, 1995 | Walt Disney Studios Motion Pictures |
| 44 | Moonstruck | $80,640,528 | 1,178 | $127,599 | 7 | Dec 18, 1987 | Metro-Goldwyn-Mayer (MGM) |
| 45 | What Happens in Vegas | $80,277,646 | 3,255 | $20,172,474 | 3,215 | May 9, 2008 | Twentieth Century Fox |
| 46 | The Wedding Singer | $80,245,725 | 2,837 | $18,865,080 | 2,821 | Feb 13, 1998 | New Line Cinema |
| 47 | 27 Dresses | $76,808,654 | 3,074 | $23,007,725 | 3,057 | Jan 18, 2008 | Twentieth Century Fox |
| 48 | 10 | $74,865,517 | 706 | $3,526,692 | 706 | Oct 5, 1979 | Warner Bros. |
| 49 | Six Days Seven Nights | $74,339,294 | 2,606 | $16,485,276 | 2,550 | Jun 12, 1998 | Walt Disney Studios Motion Pictures |
| 50 | Bridget Jones's Diary | $71,543,427 | 2,547 | $10,733,933 | 1,611 | Apr 13, 2001 | Miramax |
| 51 | Bird on a Wire | $70,978,012 | 2,008 | $15,338,160 | 1,944 | May 18, 1990 | Universal Pictures |
| 52 | Groundhog Day | $70,906,973 | 1,742 | $12,517,672 | 1,640 | Feb 12, 1993 | Columbia Pictures |
| 53 | Shallow Hal | $70,839,203 | 2,799 | $22,518,295 | 2,770 | Nov 9, 2001 | Twentieth Century Fox |
| 54 | No Strings Attached | $70,662,220 | 3,050 | $19,652,921 | 3,018 | Jan 21, 2011 | Paramount Pictures |
| 55 | Fool's Gold | $70,231,041 | 3,125 | $21,589,295 | 3,125 | Feb 8, 2008 | Warner Bros. |
| 56 | Boomerang | $70,052,444 | 2,145 | $13,640,706 | 2,127 | Jul 1, 1992 | Paramount Pictures |
| 57 | Splash | $69,821,334 | 1,186 | $6,174,059 | 829 | Mar 9, 1984 | Walt Disney Studios Motion Pictures |
| 58 | Nine Months | $69,684,532 | 1,795 | $12,522,240 | 1,458 | Jul 14, 1995 | Twentieth Century Fox |
| 59 | The Secret of My Success | $66,995,879 | 1,346 | $7,766,452 | 1,336 | Apr 10, 1987 | Universal Pictures |
| 60 | The Mexican | $66,845,033 | 3,162 | $20,108,829 | 2,951 | Mar 2, 2001 | DreamWorks Distribution |
| 61 | Down to Earth | $64,186,502 | 2,521 | $17,268,883 | 2,521 | Feb 16, 2001 | Paramount Pictures |
| 62 | Working Girl | $63,779,477 | 1,149 | $4,718,485 | 1,051 | Dec 23, 1988 | Twentieth Century Fox |
| 63 | She's All That | $63,366,989 | 2,654 | $16,065,430 | 2,222 | Jan 29, 1999 | Miramax |
| 64 | Bewitched | $63,313,159 | 3,188 | $20,131,130 | 3,174 | Jun 24, 2005 | Sony Pictures Releasing |
| 65 | The Holiday | $63,224,849 | 2,698 | $12,778,913 | 2,610 | Dec 8, 2006 | Sony Pictures Releasing |
| 66 | Forgetting Sarah Marshall | $63,172,463 | 2,872 | $17,725,330 | 2,798 | Apr 18, 2008 | Universal Pictures |
| 67 | The Wedding Planner | $60,400,856 | 2,785 | $13,510,293 | 2,785 | Jan 26, 2001 | Sony Pictures Releasing |
| 68 | The American President | $60,079,496 | 1,508 | $10,014,558 | 1,508 | Nov 17, 1995 | Sony Pictures Releasing |
| 69 | The Family Stone | $60,062,868 | 2,469 | $12,521,027 | 2,466 | Dec 16, 2005 | Twentieth Century Fox |
| 70 | Love Actually | $59,696,144 | 1,714 | $6,886,080 | 576 | Nov 7, 2003 | Universal Pictures |
| 71 | HouseSitter | $58,500,635 | 1,987 | $9,106,950 | 1,671 | Jun 12, 1992 | Universal Pictures |
| 72 | Easy A | $58,401,464 | 2,974 | $17,734,040 | 2,856 | Sep 17, 2010 | Screen Gems |
| 73 | Midnight in Paris | $56,817,045 | 1,038 | $599,003 | 6 | May 20, 2011 | Sony Pictures Classics |
| 74 | Clueless | $56,631,572 | 1,922 | $10,612,443 | 1,653 | Jul 21, 1995 | Paramount Pictures |
| 75 | Just Married | $56,127,162 | 2,769 | $17,548,993 | 2,766 | Jan 10, 2003 | Twentieth Century Fox |
| 76 | Friends with Benefits | $55,802,754 | 2,926 | $18,622,150 | 2,926 | Jul 22, 2011 | Screen Gems |
| 77 | Never Been Kissed | $55,474,756 | 2,500 | $11,836,707 | 2,455 | Apr 9, 1999 | Twentieth Century Fox |
| 78 | Ghosts of Girlfriends Past | $55,250,026 | 3,175 | $15,411,434 | 3,175 | May 1, 2009 | Warner Bros. |
| 79 | Doc Hollywood | $54,830,779 | 1,694 | $7,251,854 | 1,575 | Aug 2, 1991 | Warner Bros. |
| 80 | What Men Want | $54,611,903 | 2,912 | $18,232,087 | 2,912 | Feb 8, 2019 | Paramount Pictures |
| 81 | New Year's Eve | $54,544,638 | 3,505 | $13,019,180 | 3,505 | Dec 9, 2011 | Warner Bros. |
| 82 | Tin Cup | $53,854,588 | 2,102 | $10,128,834 | 2,012 | Aug 16, 1996 | Warner Bros. |
| 83 | Sabrina | $53,672,080 | 1,976 | $5,563,259 | 1,821 | Dec 15, 1995 | Paramount Pictures |
| 84 | Life as We Know It | $53,374,681 | 3,150 | $14,506,464 | 3,150 | Oct 8, 2010 | Warner Bros. |
| 85 | Letters to Juliet | $53,032,453 | 2,975 | $13,540,486 | 2,968 | May 14, 2010 | Summit Entertainment |
| 86 | Forces of Nature | $52,900,680 | 2,335 | $13,510,728 | 2,058 | Mar 19, 1999 | DreamWorks Distribution |
| 87 | Four Weddings and a Funeral | $52,700,832 | 1,069 | $138,486 | 5 | Mar 11, 1994 | Gramercy Pictures (I) |
| 88 | Bull Durham | $50,888,729 | 1,297 | $5,009,301 | 1,238 | Jun 17, 1988 | Orion Pictures |
| 89 | Music and Lyrics | $50,572,589 | 2,955 | $13,623,630 | 2,955 | Feb 14, 2007 | Warner Bros. |
| 90 | Overboard | $50,316,123 | 2,006 | $14,711,101 | 1,623 | May 4, 2018 | Pantelion Films |
| 91 | Serendipity | $50,294,317 | 2,610 | $13,309,241 | 2,601 | Oct 5, 2001 | Miramax |
| 92 | Legal Eagles | $49,851,591 | 1,248 | $8,043,360 | 1,248 | Jun 20, 1986 | Universal Pictures |
| 93 | Isn't It Romantic | $48,791,187 | 3,444 | $14,247,758 | 3,444 | Feb 13, 2019 | Warner Bros. |
| 94 | About Last Night | $48,637,684 | 2,253 | $25,649,011 | 2,253 | Feb 14, 2014 | Screen Gems |
| 95 | Date Movie | $48,548,426 | 2,898 | $19,076,261 | 2,896 | Feb 17, 2006 | Twentieth Century Fox |
| 96 | Just Like Heaven | $48,318,130 | 3,543 | $16,408,718 | 3,508 | Sep 16, 2005 | DreamWorks Distribution |
| 97 | The Preacher's Wife | $48,102,795 | 2,008 | $7,649,752 | 1,783 | Dec 13, 1996 | Walt Disney Studios Motion Pictures |
| 98 | Kate & Leopold | $47,121,859 | 2,467 | $9,725,408 | 2,452 | Dec 25, 2001 | Miramax |
| 99 | How to Be Single | $46,843,513 | 3,357 | $17,878,911 | 3,343 | Feb 12, 2016 | Warner Bros. |
| 100 | Practical Magic | $46,732,881 | 2,652 | $13,104,694 | 2,652 | Oct 16, 1998 | Warner Bros. |
