| TD | YD | Release
| Daily | %± YD | %± LW | Theaters | Avg | To Date | Days | Distributor
| New This Day
| Estimated
|
|---|
| 1 | - | Space Jam: A New Legacy | $13,100,000 | - | - | 3,965 | $3,303 | $13,100,000 | 1 | Warner Bros. | true | true |
| 2 | 1 | Black Widow | $8,055,534 | +60.2% | -79.6% | 4,275 | $1,884 | $113,817,205 | 8 | Walt Disney Studios Motion Pictures | false | false |
| 3 | - | Escape Room: Tournament of Champions | $3,850,310 | - | - | 2,815 | $1,367 | $3,850,310 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | F9: The Fast Saga | $2,265,250 | +87.8% | -35.3% | 3,368 | $672 | $149,484,205 | 22 | Universal Pictures | false | false |
| 5 | 3 | The Boss Baby: Family Business | $1,516,610 | +39.2% | -47.9% | 3,449 | $439 | $41,438,285 | 15 | Universal Pictures | false | false |
| 6 | 4 | The Forever Purge | $1,289,555 | +56.5% | -44.7% | 2,735 | $471 | $33,040,265 | 15 | Universal Pictures | false | false |
| 7 | - | Roadrunner: A Film About Anthony Bourdain | $781,675 | - | - | 927 | $843 | $781,675 | 1 | Focus Features | true | false |
| 8 | 5 | A Quiet Place Part II | $702,089 | +73.3% | -29.3% | 1,995 | $351 | $153,429,959 | 50 | Paramount Pictures | false | false |
| 9 | - | Pig | $376,043 | - | - | 552 | $681 | $376,043 | 1 | Neon | true | false |
| 10 | 6 | Cruella | $369,005 | +14.9% | -54.5% | 1,175 | $314 | $82,686,522 | 50 | Walt Disney Studios Motion Pictures | false | false |
| 11 | 8 | Hitman's Wife's Bodyguard | $233,039 | +26.8% | -50.8% | 1,034 | $225 | $36,131,170 | 31 | Lionsgate | false | false |
| 12 | 7 | Peter Rabbit 2: The Runaway | $185,093 | -13.7% | -56.2% | 1,117 | $165 | $38,877,412 | 36 | Sony Pictures Releasing | false | false |
| 13 | - | In the Heights | $110,000 | - | -40.5% | 418 | $263 | $28,828,518 | 36 | Warner Bros. | false | true |
| 14 | 9 | Zola | $91,565 | -8.3% | -56.9% | 533 | $171 | $4,097,203 | 17 | A24 | false | false |
| 15 | - | The Conjuring: The Devil Made Me Do It | $90,000 | - | -55% | 390 | $230 | $64,314,540 | 43 | Warner Bros. | false | true |
| 16 | 10 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $45,994 | -32.5% | -58.5% | 275 | $167 | $1,737,360 | 22 | Searchlight Pictures | false | false |
| 17 | 12 | Queen Bees | $15,147 | +12% | -25.4% | 123 | $123 | $1,740,303 | 36 | Gravitas Ventures | false | false |
| 18 | 11 | Spirit Untamed | $14,985 | -12.3% | -70.5% | 910 | $16 | $17,444,265 | 43 | Universal Pictures | false | false |
| 19 | 14 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $9,156 | +48.8% | -7.3% | 38 | $240 | $49,414,836 | 85 | FUNimation Entertainment | false | false |
| 20 | 18 | Raya and the Last Dragon | $5,997 | +162.8% | -53.5% | 41 | $146 | $54,611,577 | 134 | Walt Disney Studios Motion Pictures | false | false |
| 21 | 15 | Witnesses | $5,447 | -1.3% | -45% | 21 | $259 | $763,346 | 43 | Purdie Distribution | false | false |
| 22 | 13 | The Loneliest Whale: The Search for 52 | $4,825 | -21.8% | -56.6% | 71 | $67 | $69,123 | 8 | Bleecker Street Media | false | false |
| 23 | 16 | Werewolves Within | $4,671 | -5.3% | -41.6% | 46 | $101 | $547,020 | 22 | IFC Films | false | false |
| 24 | 17 | Dream Horse | $3,280 | +26.5% | -23.1% | 30 | $109 | $2,847,296 | 57 | Bleecker Street Media | false | false |
| 25 | 19 | Wrath of Man | $2,313 | +29% | -34.9% | 45 | $51 | $27,448,434 | 71 | United Artists Releasing | false | false |
| 26 | - | The Swimming Pool 2021 Re-release | $1,470 | - | - | 4 | $367 | $122,258 | 64 | Rialto Distribution | false | false |
| 27 | - | The Red Circle 2021 Re-release | $1,195 | - | - | 5 | $239 | $41,596 | 22 | Rialto Pictures | false | false |
| 28 | 20 | Rita Moreno: Just a Girl Who Decided to Go for It | $1,079 | +39% | -16.6% | 16 | $67 | $254,521 | 29 | Roadside Attractions | false | false |
| 29 | 22 | Casanova, Last Love | $876 | +127.5% | - | 6 | $146 | $1,840 | 3 | Cohen Media Group | false | false |
| 30 | - | The Ladykillers 2021 Re-release | $115 | - | - | 1 | $115 | $18,617 | 43 | Rialto Pictures | false | false |
