| Rank
| Release
| Gross
| Lifetime Gross
| % of Total
| Theaters
| Average
| Date
| Distributor
|
|---|
| 401 | Jason Bourne | $345 | $2,433,034 | - | 6 | $57 | Jul 27, 2016 | Universal Pictures International (UPI) |
| 402 | Contagion | $314 | $635,652 | - | 1 | $314 | Sep 9, 2011 | Warner Bros. |
| 403 | The Creator | $303 | $471,426 | - | - | - | Oct 4, 2023 | Walt Disney Pictures |
| 404 | Dan in Real Life | $296 | $70,570 | - | 1 | $296 | Feb 27, 2008 | - |
| 405 | Tooth Fairy | $295 | $472,939 | - | 1 | $295 | Jan 22, 2010 | 20th Century Fox International |
| 406 | Rio 2 | $290 | $2,574,406 | - | 1 | $290 | Apr 9, 2014 | 20th Century Fox International |
| 407 | Resident Evil: Retribution | $288 | $2,991,945 | - | 2 | $144 | Sep 12, 2012 | Sony Pictures Releasing |
| 408 | G-Force | $286 | $802,832 | - | 3 | $95 | Oct 7, 2009 | Walt Disney Pictures |
| 409 | Just Go with It | $278 | $639,198 | - | 1 | $278 | Feb 16, 2011 | Sony Pictures Releasing |
| 410 | The Invasion | $277 | $308,126 | - | 2 | $138 | Aug 29, 2007 | - |
| 411 | Despicable Me 3 | $277 | $3,411,209 | - | - | - | Jun 14, 2017 | Universal Pictures International (UPI) |
| 412 | The Possession of Hannah Grace | $274 | $1,077,436 | - | 1 | $274 | Jan 23, 2019 | Sony Pictures Releasing |
| 413 | Charlie St. Cloud | $231 | $180,765 | - | 2 | $115 | Sep 29, 2010 | United International Pictures |
| 414 | The Wolverine | $217 | $3,960,367 | - | 1 | $217 | Jul 25, 2013 | 20th Century Fox International |
| 415 | Speak No Evil | $214 | $152,492 | - | 1 | $214 | Sep 11, 2024 | Universal Pictures International (UPI) |
| 416 | Cowboys & Aliens | $213 | $709,169 | - | 2 | $106 | Aug 10, 2011 | United International Pictures |
| 417 | Bad Boys for Life | $212 | $921,124 | - | 2 | $106 | Jan 22, 2020 | Sony Pictures Releasing |
| 418 | Changeling | $208 | $20,784 | - | 2 | $104 | Jan 14, 2009 | - |
| 419 | The Angry Birds Movie 2 | $198 | $483,831 | - | 1 | $198 | Aug 21, 2019 | Sony Pictures Releasing |
| 420 | Alvin and the Chipmunks: Chipwrecked | $193 | $1,323,682 | - | 1 | $193 | Jan 8, 2012 | Warner Bros. |
| 421 | Transformers: The Last Knight | $187 | $5,646,985 | - | 1 | $187 | Jun 21, 2017 | Paramount Pictures International |
| 422 | Dracula Untold | $186 | $1,979,816 | - | 1 | $186 | Oct 15, 2014 | Universal Pictures International (UPI) |
| 423 | The Girl with the Dragon Tattoo | $176 | $223,225 | - | 1 | $176 | Feb 1, 2012 | Sony Pictures Releasing |
| 424 | Valentine's Day | $175 | $752,679 | - | 1 | $175 | Feb 12, 2010 | Warner Bros. |
| 425 | The Back-up Plan | $166 | $276,714 | - | 1 | $166 | Apr 23, 2010 | Sony Pictures Releasing |
| 426 | Jigsaw | $161 | $388,510 | - | - | - | Nov 1, 2017 | Pioneer Films |
| 427 | Zookeeper | $158 | $176,706 | - | 1 | $158 | Sep 21, 2011 | Sony Pictures Releasing |
| 428 | Paranormal Activity: The Marked Ones | $158 | $183,503 | - | 1 | $158 | Jan 29, 2014 | United International Pictures |
| 429 | Bee Movie | $155 | $322,840 | - | 1 | $155 | Jan 8, 2008 | - |
| 430 | Hall Pass | $152 | $180,151 | - | 2 | $76 | Apr 6, 2011 | Warner Bros. |
| 431 | Sherlock Holmes | $150 | $1,136,300 | - | 2 | $75 | Jan 8, 2010 | Warner Bros. |
| 432 | Captain America: The First Avenger | $149 | $3,577,307 | - | 1 | $149 | Jul 27, 2011 | United International Pictures |
| 433 | Safe House | $147 | $333,089 | - | 1 | $147 | Feb 10, 2012 | United International Pictures |
| 434 | We're the Millers | $144 | $133,435 | - | 1 | $144 | Sep 18, 2013 | Warner Bros. |
| 435 | Kick-Ass 2 | $142 | $265,146 | - | 1 | $142 | Aug 14, 2013 | United International Pictures |
| 436 | Prometheus | $139 | $1,067,040 | - | 2 | $69 | Jun 6, 2012 | 20th Century Fox International |
| 437 | Made of Honor | $134 | $334,483 | - | 1 | $134 | Jun 18, 2008 | - |
| 438 | Pitch Perfect | $131 | $68,315 | - | 2 | $65 | Oct 10, 2012 | United International Pictures |
| 439 | Carrie | $128 | $1,038,126 | - | 1 | $128 | Oct 16, 2013 | Sony Pictures Releasing |
| 440 | Uncle Drew | $109 | $515,380 | - | - | - | Jun 27, 2018 | Rafaella Films International |
| 441 | Fright Night | $106 | $317,024 | - | 1 | $106 | Sep 7, 2011 | Walt Disney Pictures |
| 442 | Horton Hears a Who! | $105 | $580,089 | - | 1 | $105 | Mar 22, 2008 | - |
| 443 | The Campaign | $103 | $229,854 | - | 1 | $103 | Aug 29, 2012 | Warner Bros. |
| 444 | The Descendants | $94 | $75,387 | - | 1 | $94 | Feb 15, 2012 | 20th Century Fox International |
| 445 | Cats & Dogs: The Revenge of Kitty Galore | $93 | $497,213 | - | 1 | $93 | Aug 18, 2010 | Warner Bros. |
| 446 | Les Misérables | $89 | $1,954,694 | - | 1 | $89 | Jan 16, 2013 | United International Pictures |
| 447 | This Means War | $77 | $758,702 | - | 1 | $77 | Feb 22, 2012 | Warner Bros. |
| 448 | Fast X | $56 | $2,866,472 | - | 1 | $56 | May 17, 2023 | Universal Pictures International (UPI) |
| 449 | Seven Pounds | $47 | $92,154 | - | 1 | $47 | Feb 4, 2009 | - |
| 450 | Cars 3 | $35 | $1,275,148 | - | - | - | Jul 26, 2017 | Walt Disney Pictures |
| 451 | Ambulance | $33 | $52,265 | - | 1 | $33 | Mar 16, 2022 | Warner Bros. |
| 452 | Christopher Robin | $16 | $620,324 | - | - | - | Aug 1, 2018 | Walt Disney Pictures |
| 453 | You Don't Mess with the Zohan | $10 | $616,592 | - | 1 | $10 | Aug 6, 2008 | - |
| 454 | Jonas Brothers: The 3D Concert Experience | $8 | $31,915 | - | 1 | $8 | Mar 4, 2009 | - |
| 455 | J. Edgar | $5 | $49,059 | - | 1 | $5 | Jan 25, 2012 | Warner Bros. |
